Fig. 2

Altered gut microbiota in NMOSD patients by their responses to MMF therapy. (A) Observed OTUs. (B) Chao1 index. (C) Shannon index. (D) Simpson index of the gut microbiota in EG and LEG samples. (E) Principal component analysis. (F) Composition of the gut microbiota at the genus levels in fecal samples in EG and LEG samples. (G) LEfSe (Linear discriminant analysis effect size) analysis showing taxa associated with therapeutic response of MMF. n = 23 for effective group (EG) and n = 11 for less-effective group (LEG). *p < 0.05