Table 1 Characteristics of the participants according to NLR and UA among AIS patients after IVT

Patients, n

139

139

138

139

Age, y

64.02 ± 11.94

63.61 ± 12.58

66.62 ± 12.45

67.35 ± 12.75

0.026

Male sex, n (%)

71(51.08)

105(75.54)

74(53.62)

103(74.10)

< 0.001

Current cigarette smoking, n (%)

42(30.22)

66(47.48)

40(28.99)

55(39.57)

0.004

Current alcohol drinking, n (%)

29(20.86)

31(22.30)

19(13.77)

23(16.65)

0.234

Time from onset to thrombolysis, h

3.00(2.62–3.70)

3.00(2.33–3.97)

3.33(2.67-4.00)

3.38(2.67-4.00)

0.081

Admission systolic BP, mm Hg

147.60 ± 19.10

147.27 ± 18.21

154.36 ± 23.36

148.44 ± 22.35

0.015

Admission diastolic BP, mm Hg

81.95 ± 12.83

82.24 ± 13.48

82.36 ± 15.15

83.78 ± 15.24

0.718

Triglycerides, mmol/L

1.07(0.85–1.44)

1.21(0.92–1.80)

1.09(0.79–1.38)

1.09(0.80–1.45)

0.014

Total cholesterol, mmol/L

4.54(3.89–5.27)

4.86(4.23–5.51)

4.52(3.81–5.22)

4.41(3.88–5.11)

0.008

LDL cholesterol, mmol/L

2.88(2.15–3.34)

3.04(2.47–3.65)

2.78(2.20–3.21)

2.70(2.22–3.27)

0.006

HDL cholesterol, mmol/L

1.16(0.95–1.38)

1.12(0.94–1.33)

1.21(1.02–1.50)

1.17(1.00-1.35)

0.049

Plasma glucose, mmol/L

6.70(5.60–8.60)

6.70(5.40–8.20)

7.35(6.40–9.30)

7.10(5.90–8.90)

< 0.001

Admission NIHSS score

8(4–12)

8(5–12)

12(7–18)

14(9–19)

< 0.001

Admission mRS score

4(3–5)

4(3–5)

5(4–5)

5(4–5)

< 0.001

History of hypertension, n (%)

99(71.22)

101(72.66)

111(80.43)

115(82.73)

0.058

History of hyperlipidemia, n (%)

58(41.73)

62(44.60)

40(28.99)

41(29.50)

0.008

History of diabetes mellitus, n (%)

26(18.71)

18(12.95)

31(22.46)

22(15.83)

0.190

History of stroke, n (%)

19(13.67)

22(15.83)

26(18.84)

25(17.99)

0.656

History of coronary heart disease, n (%)

6(4.32)

4(2.88)

5(3.62)

8(5.76)

0.665

History of atrial fibrillation, n (%)

34(24.46)

38(27.34)

51(36.96)

76(54.68)

< 0.001

Use of antihypertensive medications, n (%)

8(5.76)

10(7.19)

10(7.25)

16(11.51)

0.316

Stroke subtypes (TOAST)

< 0.001

Large artery atherosclerosis

69(49.64)

66(47.48)

52(37.68)

45(32.37)

Small vessel occlusion

35(25.18)

37(26.62)

55(39.86)

76(54.68)

Cardioembolism

28(20.14)

34(24.46)

21(15.22)

10(7.19)

Stroke of other determined etiology

5(3.60)

0(0.00)

7(5.07)

6(4.32)

Stroke of undetermined etiology

2(1.44)

2(1.44)

3(2.17)

2(1.44)