Table 1 Baseline characteristics of included participants
From: Associations of sleep disorders with serum neurofilament light chain levels in Parkinson’s disease
Variables | PD (n = 585) | Prodromal PD (n = 353) | HC (n = 175) | P values |
|---|---|---|---|---|
Age | P = 0.459 | |||
Mean ± SD | 61.94 ± 9.93 | 63.07 ± 7.52 | 61.11 ± 10.93 | |
(Minimum, maximum) | (32.20, 85.20) | (42.10, 84.30) | (31.00, 83.70) | |
Sex (n, %) | P < 0.001 | |||
Male | 341 (58.29%) | 166 (47.03%) | 111 (63.43%) | |
Female | 244 (41.71%) | 187 (52.97%) | 64 (36.57%) | |
Educate years | P < 0.001 | |||
Mean ± SD | 15.38 ± 3.57 | 16.61 ± 4.04 | 16.06 ± 2.84 | |
(Minimum, maximum) | (0.00, 26.00) | (0.00, 30.00) | (8.00, 23.00) | |
Montreal cognitive assessment | P < 0.001 | |||
Mean ± SD | 26.70 ± 2.84 | 26.70 ± 2.58 | 28.19 ± 1.09 | |
(Minimum, maximum) | (11.00, 30.00) | (11.00, 30.00) | (27.00, 30.00) | |
RBDSQ total scores | P = 0.024 | |||
Mean ± SD | 3.27 ± 2.74 | 3.39 ± 2.87 | 2.58 ± 2.14 | |
(Minimum, maximum) | (0.00, 12.00) | (0.00, 12.00) | (0.00, 11.00) | |
ESS total scores | P = 0.294 | |||
Mean ± SD | 6.17 ± 4.03 | 5.65 ± 3.46 | 5.70 ± 3.46 | |
(Minimum, maximum) | (0.00, 24.00) | (0.00, 20.00) | (0.00, 19.00) | |
Serum total NfL (pg/ml) | P = 0.005 | |||
Median | 11.90 | 11.80 | 10.60 | |
(Minimum, maximum) | (2.76, 46.60) | (3.34, 47.10) | (2.75, 51.00) |