Table 1 The characteristics of the 150 plasma samples from AIS subject patients

Gender (male/female)

109/41

Age (years)

61.4 ± 10.9[25–85]

Hypertension, n (%)

122 (81.3%)

Diabetes mellitus, n (%)

66 (44.0%)

Heart disease, n (%)

46 (30.7%)

Drinking, n (%)

71 (47.3%)

Smoking, n (%)

67 (44.7%)

Medication usage

Aspirin, n (%)

87 (58.0%)

Statins, n (%)

141 (94.0%)

Clopidogrel, n (%)

65 (43.3%)

Stroke subtype

Large artery atherosclerosis, n (%)

16 (10.7%)

Cardioembolism, n (%)

41 (27.3%)

Small vessel occlusion, n (%)

50 (33.3%)

Other determined causes, n (%)

15 (10.0%)

strokes of unknown causes, n (%)

28 (18.7%)

Hyperhomocysteinemia, n (%)

24 (16.0%)

NIHSS at admission

6 [0–25]

Total Hcy concentration (µmol·L^− 1)

16.49 ± 9.19 [4.29–62.08]

Reduced Hcy concentration (Hcy, µmol·L^− 1)

0.65 ± 0.64 [0.06–3.37]

Reduced Cys concentration (Cys, µmol·L^− 1)

9.88 ± 7.68[0.44–34.20]

Reduced CG concentration (CG, µmol·L^− 1)

58.32 ± 68.01[0.36–651]

Reduced GSH concentration (GSH, µmol·L^− 1)

28.25 ± 61.45[0.55–471]

Own oxidized Hcy concentration (HHcy, µmol·L^− 1)

0.0168 ± 0.0123 [0.0041–0.0704]

Own oxidized Cys concentration (Cyss, µmol·L^− 1)

3.76 ± 2.86 [0.0142-15.50]

The concentration ratio of Hcy/HHcy

42.72 ± 37.85 [1.78-207.38]

The concentration ratio of Cys/Cyss

4.66 ± 7.24 [0.184–46.13]