Fig. 1

Experimental design. T1-5 represent measurement time points. During T2-5 the same measurements are repeated, expect the addition of clinical examination in time point T4. The red line is the expected change in cognitive test performance on the smartphone-based cognitive test without intervention, which we expect to show a fast increase in the first ± 3 sessions followed by a slight increase over time due to a learning effect. The X’s mark how cognitive test results are hypothesized to change due to the intervention