Table 2 Characteristics of the included studies

Study

Number (IDI /C anti-TB)

Total cases

Mean age (IDI / C anti-TB)

Treatment time (weeks)

The frequency of intrathecal injection (times/week)

Li et al. [27]

47/46

93

33.51/34.21

12

2-3

Shang et al. [28]

20/20

40

39^a

8

Once every 2 days

Lu et al. [29]

32/30

62

27.8/26.3

8

2-3

Chen et al. [30]

26/11

37

42^a

8

Once every 2-4 days

Li et al. [31]

50/50

100

39.2/39.6

8

2-3

Bai et al. [32]

39/39

78

39.53/39.08

8

Once every 2 days

Yan et al. [33]

41/41

82

32.2/32.4

8

2-3

Wei et al. [34]

23/21

44

22^a

8

2-3

He et al. [35]

34/34

68

32.7/31

8

#

Fan et al. [36]

46/46

92

39.46/39.57

8

2-3

Li et al. [37]

34/34

68

40.75/40.12

4

3

Study

Number (higher-dose IDI / lower-dose IDI)

Total cases

Mean age (higher-dose IDI / lower-dose IDI)

Treatment time (weeks)

The frequency of intrathecal injection (times/week)

Dilaremu et al. [38]

36/36

72

51.5/52.1

24

Not mentioned

Meng et al. [39]

70/40

110

45/45

24

Once every 2 days

Jin et al. [40]

60/60

120

67.3/66.3

12

1

Du et al. [41]

31/31

62

34.16/32.25

24

Once every (4 ± 1) days

Zhang et al. [42]

62/58

120

45.21/46.48

12

1

Hu et al. [43]

60/52

112

40.15/39.4

24

2-3