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Table 1 Comparisons of demographics and profiles of SVD and inflammatory markers between sex

From: Sex-specific implications of inflammation in covert cerebral small vessel disease

 

Total

N = 708

Male

n = 316

Female

n = 392

P value

Age, years

62.19 ± 8.51

62.82 ± 8.89

61.96 ± 8.16

0.151

HTN

245 (34.6%)

106 (33.5%)

139 (35.5%)

0.634

DM

100 (14.1%)

41 (13.0%)

59 (15.1%)

0.449

Dyslipidemia

74 (10.5%)

19 (6.0%)

55 (14.0%)

< 0.001

Cigarette smoking

106 (15.0%)

96 (30.4%)

10 (2.6%)

< 0.001

Simple SVD score

   

0.060

1

276 (39.0%)

135 (42.7%)

141 (36.0%)

 

2 or 3

108 (15.3%)

52 (16.5%)

56 (14.3%)

 

SVD type

0.206

1

246 (34.7%)

119 (37.7%)

127 (32.4%)

 

2

47 (6.6%)

22 (7.0%)

25 (6.4%)

 

3

56 (7.9%)

29 (9.2%)

27 (6.9%)

 

4

35 (4.9%)

17 (5.4%)

18 (5.6%)

 

Homocysteine, umol/L

12.10 (10.10–14.60)

13.60 (11.80–16.20)

10.75 (9.10-12.78)

< 0.001

hsCRP, mg/dL

0.064 (0.025–0.158)

0.056 (0.025–0.156)

0.066 (0.026–0.159)

0.516

  1. Continuous variable: Mann–Whitney U test; Category variable: Fisher’s exact test or Pearson’s chi-squared test; N (%) or mean ± standard deviation or median (interquartile range)
  2. DM: diabetes mellitus; HTN: hypertension; hsCRP: high-sensitivity C-reactive protein; SVD: cerebral small vessel disease