Fig. 2
From: Plasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma
ROC curve analysis and decision curve analysis in glioma with preoperative epilepsy. A: A receiver operating characteristic (ROC) curve analysis shows that the concentration of CRYAB had a strong diagnostic power in discriminating glioma with epilepsy from glioma without epilepsy. B: and had a strong diagnostic power in discriminating epilepsy from control. C: ROC curve analysis shows that the concentration of CRYAB had no diagnostic power in discriminating intractable epilepsy from control. D: Decision curve analysis highlights the clinical benefit for the prediction of preoperative epilepsy by the decreased circulating levels of plasma CRYAB in the glioma patient with (G + E) or without preoperative epilepsy (G-E). E: Decision curve analysis highlights the clinical benefit for the prediction of epilepsy by the decreased circulating levels of plasma CRYAB in the epilepsy patient. F: The decision curves revealed that the prediction model add no net benefit for prediction intractable epilepsy (IE) by the circulating levels of plasma CRYAB