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Table 1 Mediation effect between gut microbiota and vertigo

From: Potential mechanisms of gut microbiota influence on different types of vertigo: a bidirectional Mendelian randomization and mediation analysis

Benign Paroxysmal Vertigo (Outcome)

     

Exposure

Mediator

Total effect

BetaA

BetaB

Mediation effect

Mediation effect proportion

family Rhodospirillaceae

Major depression

-0.073

-0.099

0.212

-0.021

28.77%

class Lentisphaeria/

order Victivallales

Obesity

0.059

0.186

0.044

0.008

13.90%

genus Bifidobacterium

HbA1c

-0.092

-0.085

0.127

-0.011

11.79%

family Bifidobacteriaceae/

order Bifidobacteriales

HbA1c

-0.082

-0.073

0.127

-0.009

11.36%

Vertigo of Central (Outcome)

     

Exposure

Mediator

Total effect

BetaA

BetaB

Mediation effect

Mediation effect proportion

phylum Actinobacteria

Interleukin-18 levels

0.427

0.066

0.424

0.028

6.56%

genus Alloprevotella

Major depression

0.220

0.016

0.904

0.014

6.51%