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Table 1 Data of patient background and pre-medication

From: Relative score of early neurological deterioration in perforator artery infarction: a retrospective study

END

+ (27)

- (174)

P-value

 

N

%

N

%

 

Sex (male)

15

55.6

101

58.0

0.807

Age

76.5 ± 11.7

68.2 ± 13.4

0.003

Age > 69 (mean age: 69)

23

85.2

89

51.1

< 0.001

Body height (cm)

161.6 ± 9.4

162.9 ± 9.2

0.473

Body weight (kg)

59.1 ± 13.0

64.1 ± 14.3

0.093

BMI (kg/m2)

22.2 ± 3.6

23.9 ± 4.0

0.039

BMI (kg/m2) < 23.8 (mean BMI: 23.8)

22

81.5

80

45.9

< 0.001

Smoking habit

4

14.8

43

24.7

0.333

HT

24

88.9

153

87.9

1.000

DM

11

40.7

69

39.7

0.915

DL

21

77.8

119

68.4

0.324

Ischemic heart disease

4

14.8

17

9.8

0.495

Af

2

7.4

13

7.5

1.000

History of stroke

6

22.2

22

12.6

0.181

Malignancy

1

3.7

6

3.4

1.000

Onset to arrival duration (hour)

12(12–48)

12(4.5–42)

0.368

Pre-medication

     

Anti-coagulant

1

3.7

11

6.3

1.000

Anti-platelet

18

66.7

37

21.3

< 0.001

Calcium channel blocker

13

48.1

51

29.3

0.051

Angiotensin II receptor blocker

6

22.2

36

20.7

0.855

Angiotensin-converting-enzyme inhibitor

1

3.7

3

1.7

0.441

Diuretic

1

3.7

6

3.4

1.000

Statin

7

25.9

30

17.2

0.279

Dipeptidyl peptidase 4 inhibitor/Glucagon-like peptide-1

6

22.2

20

11.5

0.122

Radiological finding

     

Lesion size on initial MRI

11.2 ± 6.4

14.4 ± 6.95

0.009

Lesion size over 15 mm on initial MRI

9

33.3

32

18.3

0.076

Infarct lesion; pons

7

25.9

55

31.6

0.552

Infarct lesion; internal capsule

4

14.8

38

21.8

0.611

Infarct lesion; corona radiata

15

55.5

67

38.5

0.093

Infarct lesion; thalamus

1

3.7

14

8.0

0.698

Treatment

     

Clopidogrel loading

20

74.0

161

92.5

0.003

Outcome

     

Hospital stay day

26(21–38)

15(12–21)

< 0.001

Modified Rankin Scale

2(1–4)

1(0–2)

< 0.001

Modified Rankin Scale ≤0–2

15

55.6

154

88.5

< 0.001

Transfer to rehabilitation hospital

24

88.9

45

31.2

< 0.001

  1. Abbreviation: BMI, body mass index; HT, hypertension; DM, diabetes; DL, dyslipidemia; Af, atrial fibrillation; Mean age/BMI of this cohort was 69 and 23.8, respectively. Data are expressed as mean ± SD, except Hospital stay and modified ranking scale are expressed as median and interquartile range