Table 3 Clinical examinations of the patients with isolated RBD with and without blunted tachycardia

Autonomic nervous examination

SCOPA-AUT, Total^a

9.4 ± 6.9

11.8 ± 9.4

8.0 ± 4.5

0.086

0.549

 Gastrointestinal^a

2.7 ± 2.5

3.3 ± 3.1

2.4 ± 2.0

0.302

0.326

 Urinary^a

5.0 ± 2.9

6.1 ± 3.3

4.3 ± 2.4

0.049

0.633

 Cardiovascular^a

0.52 ± 0.97

0.75 ± 1.06

0.38 ± 0.90

0.240

0.372

 Thermoregulatory^a

0.50 ± 0.99

0.75 ± 1.29

0.35 ± 0.75

0.205

0.402

 Pupillomotor^a

0.29 ± 0.60

0.31 ± 0.60

0.27 ± 0.60

0.823

0.070

 Sexual^a

0.36 ± 1.14

0.56 ± 1.63

0.23 ± 0.71

0.368

0.284

DAT-SPECT

 Striatum, right

3.91 ± 1.31

3.80 ± 1.23

3.98 ± 1.37

0.668

-0.132

 Striatum, left

3.92 ± 1.20

3.83 ± 1.13

3.98 ± 1.26

0.684

-0.126

 Striatum, average

3.92 ± 1.22

3.81 ± 1.17

3.98 ± 1.27

0.668

-0.132

¹²³I-MIBG

 H/M, early^b

1.52 ± 0.21

1.39 ± 0.13

1.61 ± 0.22

0.003

-1.089

 H/M, early < 2.28 [n, %]^b

35 [100.0%]

14 [100.0%]

21 [100.0%]

N/A

N/A

 H/M, delayed^b

1.35 ± 0.31

1.18 ± 0.11

1.46 ± 0.34

0.005

-1.017

 H/M, delayed < 1.91 [n, %]^b

33 [94.3%]

14 [100.0%]

19 [90.5%]

0.234

N/A

 Washout ratio [%]^b

35.9 ± 11.3

40.3 ± 16.0

33.0 ± 5.5

0.063

0.648

Cognitive function

 MMSE score

28.0 ± 2.3

27.2 ± 3.0

28.4 ± 1.4

0.106

-0.506

 MMSE score < 24 [n, %]

2 [4.7%]

1 [5.9%]

1 [3.4%]

0.757

N/A

 FAB score

15.3 ± 2.3

14.8 ± 2.3

15.5 ± 2.2

0.356

-0.286

 FAB score < 12 [n, %]

2 [4.7%]

1 [5.9%]

1 [3.4%]

0.757

N/A

 MoCA score

24.7 ± 2.8

24.4 ± 2.8

25.0 ± 2.9

0.535

-0.192

 MoCA score < 23 [n, %]

9 [20.9%]

5 [29.4%]

4 [15.4%]

0.269

N/A

Psychiatric symptoms

 Minor hallucinations [n, %]

18 [41.9%]

10 [58.8%]

8 [30.8%]

0.068

N/A