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Table 1 Demographic characteristics of arteriovenous malformation

From: Stereotactic radiosurgery alone for brain arteriovenous malformations: a single-institute experience

Variable

Total

n (%)

SMG I-II

n (%)

SMG III-IV

n (%)

P value

201

145

56

Sex

   

0.813†

 Male

123 (61.2)

88 (60.7)

35 (62.5)

 

 Female

78 (38.8)

57 (39.3)

21 (37.5)

 

Age, years

   

0.182‡

 Range

1–75

1–75

7–71

 

 Mean ± SD

31.4 ± 1.1

32.4 ± 1.4

29.0 ± 2.0

 

Hemorrhage

   

0.282†

 Occur

102 (50.7)

77 (53.1)

25 (44.6)

 

Preoperative mRS

   

0.125†

 1–2

59 (29.4)

47 (32.4)

12 (21.4)

 

 3–5

142 (70.6)

98 (67.6)

44 (78.6)

 

RBAS

   

< 0.001†*

 ≤1

84 (41.8)

77 (53.1)

7 (12.5)

 

 1.01–1.50

68 (33.8)

52 (35.9)

16 (28.6)

 

 1.51-2.00

25 (12.4)

10 (6.9)

15 (26.8)

 

 >2

24 (11.9)

6 (4.1)

18 (32.1)

 

Location

   

< 0.001†*

 Superficial

112 (55.7)

90 (62.1)

22 (39.3)

 

 Deep

65 (32.3)

34 (23.4)

31 (55.4)

 

 Posterior

24 (11.9)

21 (14.5)

3 (5.4)

 

Lobe(s)

   

0.332†

 Single

176 (87.6)

129 (76.8)

47 (81.8)

 

 Multi

25 (12.4)

16 (23.2)

9 (18.2)

 

Lesion diameter, cm

   

< 0.001‡*

 Range

0.6–7.7

0.6–5.5

0.8–7.7

 

 Mean ± SD

2.4 ± 0.1

2.0 ± 0.1

3.4 ± 0.2

 

Lesion volume, cm3

   

0.001‡*

 Range

0.07-133.18

0.07–29.40

0.11-133.18

 

 Mean ± SD

6.4 ± 1.1

3.0 ± 0.3

15.2 ± 3.5

 

Venous drainage

55 (27.4)

29 (20.0)

26 (46.4)

< 0.001†*

 Aneurysm

15 (7.5)

10 (6.9)

5 (8.9)

NA

Treatment

   

0.641†

 Single

169 (84.1)

123 (84.8)

46 (82.1)

 

 Multi

32 (15.9)

22 (15.2)

10 (17.9)

 

Margin dose, Gy

   

0.001‡*

 Range

8–25

12–25

8–24

 

 Mean ± SD

15.6 ± 0.2

16.1 ± 0.2

14.3 ± 0.4

 

Follow up

    

 Obliteration

74 (36.8)

61 (42.1)

13 (23.2)

0.013†*

 Hemorrhage

24 (11.9)

14 (9.6)

10 (17.9)

0.108†

 Death

5 (2.5)

5 (3.4)

0 (0)

NA

  1. mRS modified Rankin Scale, NA not available, RBAS radiosurgery-based AVM score, SD standard deviation, SMG Spetzler-Martin grade
  2. *P < 0.05.
  3. † Chi-square test
  4. ‡ Independent sample t-test