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Table 1 Comparisons of baseline and clinical characteristics between favorable and unfavorable outcome group

From: Association of critical hypoperfusion biomarkers on CT with futile recanalization and poor outcome after mechanical thrombectomy in acute ischemic stroke

Factor

All patients

N = 79

Favorable

mRS ≤ 2

N = 37

Unfavorable

mRS>2

N = 42

Χ2/t/U

P value

Age, mean ± SD

62.96 ± 11.33

61.56 ± 10.16

64.19 ± 12.32

1.027

0.301

Females/Males, n

34/45

12/25

22/20

3.193

0.074

Hypertension, n (%)

55(69.62)

28(75.67)

27(64.29)

1.207

0.272

Diabetes, n (%)

19(24.05)

8(21.62)

11(26.19)

0.225

0.635

Ischemic heart disease, n (%)

10(12.66)

4(10.81)

6(14.29)

0.215

0.643

Atrial fibrillation, n (%)

27(34.17)

10(27.03)

17(40.48)

1.582

0.209

TIA, n (%)

5(6.33)

3(8.11)

2(4.76)

0.412

0.521

Alcohol intake, n (%)

21(26.58)

8(21.62)

13(30.95)

0.878

0.349

History of smoking, n (%)

27(34.18)

13(35.14)

14(33.33)

0.028

0.866

INR, mean ± SD

1.07 ± 0.19

1.06 ± 0.18

1.08 ± 0.20

0.012

0.913

IV thrombolysis, n (%)

22(27.85)

11(29.73)

11(26.19)

0.123

0.726

Admission NIHSS,

Median (IQR)

11(8–14)

11(7–14)

11(10–14)

-1.623

0.105

OTI, Median (IQR)

7.7(4.75-11.00)

7.43(4.32–11.23)

7.88(5.95–10.83)

-0.757

0.449

OTR, Median (IQR)

12.53(8.37–17.5)

11.78(8.5-15.82)

11.75(9-16.55)

-0.418

0.676

Reperfusion grade, n (%)

 

0.177

0.764

 2b

34(43.04)

15(40.54)

19(45.24)

  

 3

45(56.96)

22(59.46)

23(54.76)

  

Location of occlusion, n (%)

 

0.944

0.624

 MCA

59(74.68)

27(72.97)

32(76.19)

  

 ICA

12(15.19)

7(18.92)

5(11.90)

  

 T-type

8(10.13)

3(8.11)

5(11.90)

  

TOAST, n (%)

 

3.516

0.172

Large-artery atherosclerosis

53(67.09)

28(75.68)

25(59.52)

  

Cardioembolism

23(29.11)

7(18.92)

16(38.10)

  

Other determined etiology

2(2.53)

1(2.70)

1(2.38)

  

Undetermined etiology

1(1.27)

1(2.70)

0(0)

  

Hemorrhagic transformation, n (%)

16(20.25)

7(18.92)

9(21.43)

0.077

0.782

sICH, n(%)

4(5.06)

1(2.70)

3(7.14)

0.142

0.677

Death, n (%)

9(11.39)

0(0)

9(21.43)

8.948

0.003

  1. IQR, Interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; INR = international normalized ratio; TIA = transient ischemic attack; OTI = onset-to-image time; OTR = onset-to-reperfusion time; MCA, Middle cerebral artery; ICA, Internal carotid artery; sICH = symptomatic intracerebral hemorrhage. TOAST = Trial of Org 10,172 in Acute Stroke Treatment