Table 1 The drugs/drug components with their molecular weight, drug class, and prescription prevalence in each cohort
From: Highly prevalent geriatric medications and their effect on β-amyloid fibril formation
ID | Drug name | Chemical name | Molecular weight | Drug class | Prescription prevalence (% of population) | ||
|---|---|---|---|---|---|---|---|
ND | MCI | AD | |||||
D1 | Aspirin | Acetylsalicylic acid | 180.16 | Anti-inflammatory | 56.57 | 53.50 | 46.10 |
D2 | Tylenol | 4-Acetamidophenol | 151.17 | Anti-inflammatory | 30.26 | 28.07 | 43.75 |
D3 | Lipitor | Atorvastatin hemicalcium | 1199.473 | Anti-Cholesterol | 21.49 | 30.7 | 25.70 |
D4 | Vitamin D/D3 | Cholecalciferol | 384.64 | Vitamins & minerals | 39.04 | 42.10 | 36.71 |
D5 | Levothyroxine | levothyroxine | 776.87 | Anti-thyroid | 21.05 | 14.91 | 8.59 |
D6 | Prilosec | Omeprazole | 345.417 | Proton pump inhibitor | 19.73 | 23.68 | 18.75 |
D7 | Lisinopril | Lisinopril Dihydrate | 423.51 | Anti-hypertensive | 17.98 | 12.28 | 17.97 |
D8 | Metformin | Metformin hydrochloride | 165.63 | Anti-diabetic | 13.59 | 7.02 | 4.84 |
D9 | Colace | Dioctyl sulfosuccinate | 444.56 | Anti-constipation | 11.40 | 8.77 | 10.15 |
D10 | Eliquis | Apixaban | 459.51 | Anti-coagulant | 8.66 | 13.56 | 12.03 |
D11 | Melatonin | Tamsulosin hydrochloride | 232.28 | Anti-insomnia | 9.64 | 8.77 | 20.16 |
D12 | Flomax | Clopidogrel hydrogensulfate | 444.971 | Alpha blocker | 8.26 | 10.17 | 3.01 |
D13 | Plavix | Clopidogrel | 419.89 | Anti-platelet | 8.27 | 7.63 | 4.51 |
D14 | Vitamin C | L-Ascorbic acid | 176.12 | Vitamins & minerals | 9.21 | 10.52 | 4.69 |
D15 | Lopressor | Metoprolol Tartrate | 684.81 | Anti-hypertensive | 9.21 | 14.04 | 10.94 |
D16 | Calcium | Calcium Acetate | 176.181 | Vitamins & minerals | 11.40 | 12.28 | 6.25 |
D17 | Cozaar | Losartan potassium | 464.031 | Anti-hypertensive | 9.21 | 14.91 | 7.81 |
D18 | Norvasc | Amlodipine | 408.88 | Anti-hypertensive | 8.33 | 14.91 | 10.93 |