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Table 5 Clinical characteristics and features of patients with NMDAR positive grouped by the change of mRS

From: Efficacy of double filtration plasmapheresis in the treatment of steroid and/or IVIG unresponsive neuronal surface antibodies associated autoimmune encephalitis

mRS change (ΔmRS) = mRS (pre) – mRS (post)

P value

Parameter

No respond and worse (ΔmRS = 0) (-1,0)

Improvement (ΔmRS ≥ 1) (1,2)

N

6

10

 

Age (range)

25.5 (17–35)

28.5 (16–59)

0.957

Gender (male %)

33.3%

50%

0.633

Neoplasm (Ovarian teratoma or tumor)

50%

20%

0.299

Serum antibody positive

4

7

1.000

CSF antibody positive

6

10

0.267

Both serum and CSF antibody positive

4

7

1.000

Period from onset to DFPP (days)

67.0 ± 69.6

99.4 ± 70.1

0.433

Plasma exchange volume of DFPP (ml/kg)

47.5 ± 9.8

53.2 ± 12.2

0.325

DFPP circles (IQR)

3.5 (3,4)

3.5 (3,5)

0.606

mRS pre (IQR)

5 (3.75, 5)

5 (4.75, 5)

0.474

mRS post (IQR)

5 (3.75, 5.25)

4 (3.75, 4)

0.041