Table 2 Symptoms and signs of LEMS and cerebellar ataxia [6, 8]
Symptom | LEMS | Cerebellar ataxia |
|---|---|---|
Proximal leg weakness | Yes | No |
Dry Mouth | Yes | No |
Diplopia | Late | Early |
Gait Abnormality | Often | Yes |
Limb ataxia | No | Yes |
Truncal Ataxia | No | Yes |
VGCC Abs | Yes > 85% | Infrequent |
Neurophysiologic Testing | Abnormal presynaptic neuromuscular transmission. | Normal |