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Table 5 Comparison of general data, laboratory tests, MoCA scores

From: Alterations in spontaneous brain activity of maintenance hemodialysis patients with restless legs syndrome: a cross-sectional case-control study

 

MHD-nRLS

(n = 27)

MHD-RLS

(n = 27)

t/Z/χ2

P value

Age(years)

48.4 ± 7.9

52.8 ± 10.4

1.731

0.089a

 

Gender(male/female)

14/13

12/15

0.297

0.586c

 

Education(years)

9.0(6.0,12.0)

9.0(6.0,12.0)

-0.638

0.523b

 

HD duration(months)

31.0(24.0,43.0)

36.0(24.0,60.0)

-0.663

0.507b

 

Hypertension(n%)

23(85.2)

23(85.2)

0.000

1.000c

 

Diabetes(n%)

16(59.3)

20(74.1)

1.333

0.248 c

 

MoCA(score)

27.0(26.0,27.0)

26.0(26.0,27.0)

-0.793

0.950b

 

Kt/V (ml-s-l/1.73m2)

1.4(1.3,1.5)

1.4(1.3,1.5)

-0.063

0.276b

 

BUN(mmol/L)

19.9(15.9,23.7)

22.3(18.7,25.4)

-1.168

0.243b

 

UA(umol/L)

344.9 ± 96.4

347.4 ± 133.5

0.938

0.938a

 

Cr(umol/L)

1184.0 ± 185.9

1199.3 ± 193.2

0.767

0.767a

 

K+(mmol/L)

4.3 ± 1.0

4.7 ± 0.7

0.147

0.147a

 

Na2+(mmol/L)

140.2 ± 3.7

140.5 ± 3.8

0.745

0.745a

 

Ca2+(mmol/L)

2.2 ± 0.3

2.2 ± 0.2

0.540

0.591a

 

P(mmol/L)

1.9 ± 0.5

1.9 ± 0.6

-0.072

0.943a

 

WBC(109/L)

5.9(5.4,5.9)

5.9(5.2,6.1)

-0.273

0.785b

 

CRP(mg/L)

4.2(2.1,16.5)

5.5(1.8,16.5)

-0.225

0.822b

 

RBC(1012/L)

3.4 ± 0.8

3.3 ± 0.9

-0.356

0.723a

 

Hb(g/L)

110.0(103.0,122.0)

101.0(77.0,107.0)

-3.281

0.001b

 

Hct(%)

30.2 ± 6.2

30.8 ± 7.1

0.323

0.748a

 

TP(g/L)

61.6 ± 10.3

65.2 ± 8.1

1.409

0.165a

 

Alb(g/L)

36.8 ± 6.6

37.9 ± 5.9

0.630

0.532a

 

TC(mmol/L)

3.9(3.0,4.7)

4.2(3.3,4.8)

-0.579

0.563b

 

TG(mmol/L)

1.5 ± 0.6

1.6 ± 0.6

-0.571

0.610a

 

AST(U/L)

13.0(11.0,19.0)

14.5(11.3,18.0)

-0.069

0.945b

 

ALT(U/L)

9.7(6.7,13.1)

11.0(10.0,12.9)

-1.524

0.127b

 

HDL-C(mmol/L)

1.1 ± 0.3

0.9 ± 0.2

-1.757

0.051a

 

LDL-C(mmol/L)

1.8(1.5,2.6)

1.9(1.5,2.5)

-0.536

0.592b

 

ALP(U/L)

74.0(65.0,97.0)

83.0(64.0,98.6)

-0.917

0.359b

 

PTH(g/L)

239.0(138.8,423.7)

221.0(158.4,430.8)

-0.026

0.979b

 

Serum iron(umol/L)

10.5 ± 3.6

9.7 ± 3.0

-0.859

0.394a

 

TIBC(umol/L)

32.6 ± 10.1

40.0 ± 10.7

2.646

0.011a

 

Serum ferritin(ng/mL)

75.4(61.1,174.4)

99.4(47.3,158.5)

-0.043

0.966b

 

Folate(ng/mL)

4.6(3.5,9.1)

6.9(4.8,20.0)

-2.282

0.022b

 

VitB12(pg/mL)

578.3 ± 363.3

733.5 ± 292.9

1.729

0.090a

 
  1. a Independent Samples t-test; b Mann-Whitney U-test; c Chi-square test
  2. HD: duration: Hemodialysis duration; MoCA: Montreal Cognitive Assessment; BUN: Blood urea nitrogen; UA: Uric acid; WBC: White blood cell; RBC: Red blood cell; TC: Total cholesterol; TP: Total protein; ALP: Alkaline phosphatase; HDL-C: High-density lipoprotein cholesterol: LDL-C: Low-density lipoprotein cholesterol; PTH: Parathyroid hormone; TIBC: Total iron binding force;; Kt/V: Urea clearance index