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Table 8 Association between selenium and selenoproteins levels with clinical data of epileptic patients

From: Correlation between selenium levels and selenoproteins expression in idiopathic generalized epilepsy: a study from Karachi

  

Selenium (µmol/ml)

 

GPx1

(ng/ml)

 

TRxR1

(ng/ml)

 

SEPW1

(ng/ml)

 

Clinical Variables

n

Mean±SD

p-value^

Median (IQR)

p-value$

Median (IQR)

p-value$

Median (IQR)

p-value$

Duration of Seizers (min)

 ≤ 5minutes

21

37.5 ± 1.9

0.864

29.8 (22.1–43.5)

0.197

1.3 (1.0–1.4)

0.455

1.8 (1.0–3.1)

0.982

 > 5minutes

9

37.6 ± 2.2

 

37.0 (24.8–66.9)

 

1.2 (1.0–1.3)

 

1.6 (1.0–2.9)

 

Total number of attacks

 ≤ 5

20

37.6 ± 2.1

0.832

34.4 (26.2–48.6)

0.033

1.2 (1.0–1.3)

0.538

2.1 (1.0–3.2)

0.379

 > 5

10

37.4 ± 1.8

 

23.0 (16.5–35.7)

 

1.3 (1.0–1.4)

 

1.7 (1.0–2.3)

 

Frequency of epileptic episode

 Once a month

17

37.2 ± 1.8

0.237

37.0 (23.4–56.5)

0.155

1.2 (1.0–1.3)

0.558

1.6 (0.8–2.9)

0.439

 Once a week

13

38.0 ± 2.1

 

27.0 (19.9–34.1)

 

1.3 (1.1–1.4)

 

1.9 (1.4–3.1)

 

Frequency of seizures becoming

 Less Frequent

14

37.7 ± 1.5

0.696

34.4 (25.2–45.8)

0.442

1.3 (1.1–1.4)

0.454

2.5 (1.5–4.1)

0.051

 Frequent Seizures

16

37.4 ± 2.3

 

29.3 (18.1–47.1)

 

1.2 (1.0–1.3)

 

1.6 (0.7–2.2)

 

Family history of seizure

 Yes

10

37.7 ± 2.2

0.722

35.9 (25.4–52.1)

0.281

1.1 (0.8–1.3)

0.086

2.0 (1.1–3.0)

0.930

 No

20

37.5 ± 1.9

 

29.8 (21.4–44.3)

 

1.3 (1.1–1.4)

 

1.8 (1.0–3.0)

 

Reason for triggering of seizures

 No Reason

23

37.3 ± 1.8

0.303

32.6 (22.7–40.2)

0.327

1.2 (1.1–1.3)

0.590

1.9 (0.9–3.0)

0.713

 Stress

7

38.2 ± 2.4

 

45.2 (24.1–55.7)

 

1.3 (0.7–1.4)

 

1.6 (1.1–2.9)

 
  1. ^p-value refers to independent t-test
  2. $p-value refers to Mann-Whitney U test