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Table 1 Scores of our patient over time

From: Successful pregnancy of an SMA type 3 sitter on Nusinersen therapy - a case report

Nusinersen –

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HFMSE (66)

RULM-r (37)

RULM-l (37)

VC (l)

HG-r (kg)

HG-l (kg)

MIP (cmH2O)

MEP (cmH2O)

1

Baseline

23

31

30

3,22

-

-

-

-

2

-

-

-

-

-

-

-

-

3

-

-

-

-

-

-

-

-

4

33

30

30

3,28

-

-

-

-

5

30

31

31

3,32

-

-

-

-

6

-

-

-

3,32

-

-

-

-

7

33

31

31

3,49

-

-

121

71

8

18 months therapy

33

30

30

3,50

11

10

114

72

9

33

30

31

3,35

-

-

110

63

10

32

32

32

3,38

11

10

115

76

11

28

32

31

3,35

10

9

142

78

12

32

32

33

3,33

9

8

142

74

13

38 months therapy

31

32

32

3,20

10

8

123

70

25th week of pregnancy

30

32

32

3,32

9

8

129

64

14

32

28

28

3,22

11

10

117

56

15

-

-

-

-

-

-

-

-

16

11 months after interruption

30

29

29

3,20

12

10

140

62

17

30

29

29

-

12

10

145

65

18

26

25

28

-

11

10

123

67

19

27

27

28

3,26

12

11

139

72

20

26

27

27

-

12

11

142

62

  1. HFMSE - expanded Hammersmith Functional Motor Scale; RULM-r/l - Revised Upper Limb Module for SMA, right or left side; HG-r/l – Handgrip right or left side; MIP – maximum inspiratory pressure - maximum expiratory pressure; VC - Vital capacity