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Table 1 MR analysis of immune cells and malignant brain tumors

From: Role of T cell metabolism in brain tumor development: a genetic and metabolic approach

Exposure

Method

Nsnp

Beta

Se

P value

Pleiotropy

Heterogeneity

HLA DR on HLA DR + CD8 + T cell

IVW

20

-0.216

0.082

0.0085

0.576

0.498

CD127-CD8 + T cell Absolute Count

IVW

13

-0.207

0.079

0.0087

0.448

0.805

Naïve CD8 + T cell Absolute Count

IVW

28

-0.034

0.014

0.0146

0.795

0.278

Naïve CD8 + T cell %T cell

IVW

28

-0.030

0.012

0.0152

0.282

0.858

CD28-CD8 + T cell %CD8 + T cell

IVW

23

-0.199

0.085

0.0190

0.655

0.934

Secreting CD4 regulatory T cell Absolute Count

IVW

23

-0.058

0.027

0.0290

0.599

0.060

Resting CD4 regulatory T cell Absolute Count

IVW

25

0.122

0.062

0.0473

0.449

0.337