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Table 3 The clinical characteristics of the three patients of MM with GBS

From: Guillain-Barré syndrome in patients with multiple myeloma: three cases report and literature review

 

Sex/age

Type of M protein

treatment regimens of MM

Interval from diagnosis of MM to GBS

Antecedent infections

Antecedent spinal surgery

Treatment of GBS

Outcome of GBS

Case 1

M/68

IgA λ

VRD, ASCT and lenalidomide

22 m

Yes

Yes

IVIG

Die

Case 2

F/70

IgA κ

PLD

4 m

Yes

Yes

IVIG

Independent transfer from bed to chair

Case 3

F/70

IgA λ

VRD, RD

6 m

No

Yes

IVIG

Some residual numbness of legs

  1. MM, multiple myeloma; GBS, Guillain-Barré syndrome; VRD, bortezomib, lenalidomide and dexamethasone; ASCT, autologous stem cell transplantation; PLD, bortezomib, liposomal doxorubicin, and dexamethasone; RD, lenalidomide and dexamethasone; IVIG, intravenous immunoglobulins