Table 2 Factors associated with early neurological deterioration
Unadjusted univariate analysis | Adjusted multivariate analysis* | |||
|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Age (years) | 1.011 (0.998–1.024) | 0.088 | - | |
Sex, male | 0.882 (0.636–1.222) | 0.450 | - | |
Hypertension | 1.257 (0.908–1.739) | 0.168 | ||
Diabetes mellitus | 1.147 (0.823–1.598) | 0.418 | ||
Hyperlipidemia | 0.891 (0.582–1.366) | 0.598 | ||
Atrial fibrillation | 1.172 (0.669–2.053) | 0.578 | ||
Smoking history | 0.964 (0.570–1.630) | 0.891 | ||
Previous stroke history | 1.817 (1.223–2.699) | 0.003 | 1.728 (1.159–2.578) | 0.007 |
Previous thrombotic | 1.319 (0.931–1.870) | 0.119 | ||
Previous statin | 1.383 (0.977–1.958) | 0.067 | - | |
Initial NIHSS score | 1.037 (0.998–1.077) | 0.062 | 1.034 (0.995–1.076) | 0.089 |
IV tPA | 0.974 (0.590–1.608) | 0.917 | ||
EVT | 0.902 (0.468–1.737) | 0.757 | ||
TOAST classification | ||||
Large artery atherosclerosis | 1 (Reference) | |||
Small vessel disease | 1.202 (0.824–1.754) | 0.340 | ||
Cardioembolism | 0.716 (0.435–1.177) | 0.188 | ||
Undetermined | 0.973 (0.362–2.615) | 0.956 | ||
Other determined | 0.879 (0.517–1.497) | 0.636 | ||
Lab findings | ||||
Total cholesterol (mg/dL) | 0.999 (0.997–1.002) | 0.601 | ||
Triglyceride (mg/dL) | 1.000 (0.999–1.001) | 0.701 | ||
HDL-C (mg/dL) | 0.998 (0.989–1.007) | 0.693 | ||
LDL-C (mg/dL) | 1.000 (0.997–1.003) | 0.819 | ||
Hba1c (%) | 0.940 (0.842–1.051) | 0.278 | ||
D-Dimer (ng/mL) | 1.000 (1.000–1.001) | 0.465 | ||
FMD (%) | 0.888 (0.818–0.965) | 0.005 | 0.889 (0.818–0.965) | 0.005 |