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Table 2 Prognostic risk factors associated with poor functional outcomes

From: Key prognostic risk factors linked to poor functional outcomes in cerebral venous sinus thrombosis: a systematic review and meta-analysis

Factors

N

Output

Effect size

95% CI

I2

P value

P value for Meta-regression

Demographic

 Age

37

lnOR

0.98

0.53–1.43

0.987

0.000*

 

 Gender (Male)

6

OR

2.14

0.52–8.77

0.922

0.290

0.243

Type of stroke

 Intracranial hemorrhage

25

OR

3.79

2.77–5.20

0.761

0.000*

0.214

 Ischemic infarction

8

OR fix

3.18

2.40–4.23

0.200

0.000*

0.032*

Clinical manifestation (general)

 Headache

8

OR fix

0.22

0.17–0.29

0.000

0.000*

0.175

 Seizure

14

OR

2.74

1.76–4.27

0.796

0.000*

 

Clinical manifestation (neurological specific)

 Focal deficit

13

OR fix

4.72

3.86–5.78

0.388

0.000*

0.526

 Coma

12

OR

11.60

6.12–21.98

0.854

0.000*

 

 Consciousness disorder

7

OR

7.07

4.15–12.04

0.740

0.000*

 < 0.001*

 NIHSS

4

lnOR

1.69

(-)0.09–3.47

0.987

0.060

 

Blood Biomarkers

 NLR

7

lnOR

1.72

0.96–2.47

0.963

0.000*

0.015*

 Lymphocyte

5

cohens'd fix

−0.63

(-)0.78-(-)0.47

0.184

0.000*

 

 D-dimer

4

lnOR

1.34

0.87–1.80

0.778

0.000*

 

 CRP

3

lnOR

2.99

(-)0.40–6.37

0.991

0.080

 

Radiology image

 Parenchymal lesion

5

OR

4.71

1.12–19.84

0.900

0.030*

0.379

 Deep cerebral venous thrombosis

8

OR

6.30

2.92–13.63

0.719

0.000*

0.390

Complication

 Cancer

6

OR fix

3.87

2.95–5.07

0.424

0.000*

 

 Blood glucose level

5

OR

3.52

1.61–7.68

0.937

0.000*

 

 Hemoglobin/anemia

5

OR

1.61

0.96–2.69

0.988

0.070

 

 Blood pressure

5

OR

7.53

0.55–103.77

0.984

0.130

0.051

  1. *Statistical significant