Table 1 Clinical characteristics for the patients
Age at diagnosis | Sex | MG duration | Abs | Pathology of thymus | Thymectomy | Underlying disease | Skeletal muscle weakness of MG | Triggers for MC | The times of MC onset | Treatment before MC | |
|---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | 49 | Female | 5 months | Ach-R-Ab、Titin-Ab、RyR-Ab | Thymoma | Bulbar, respiratory and limb muscles | No obvious precipitant | 1 | CS 8 mg, Pyd 60 mg t.i.d, IVMP, IVIG | ||
Case 2 | 42 | Female | 14 years | Ach-R-Ab、Titin-Ab | Thymoma | HTN | Ocular, bulbar, respiratory and limb muscles | Upper respiratory infection | 1 | CS 8 mg, Pyd 60 mg t.i.d, MMF 250 mg b.i.d, IVMP, IVIG | |
Case 3 | 32 | Male | 2 years | Ach-R-Ab、Titin-Ab | Thymoma | Yes | Ocular, respiratory and limb muscles | Aspiration pneumonia | 1 | CS 20 mg, Pyd 60 mg t.i.d, tac 2 mg, IVMP, IVIG | |
Case 4 | 27 | Female | 3 years | Ach-R-Ab、Titin-Ab | Thymic hyperplasia | Yes | Ocular, bulbar, neck, respiratory and limb muscles | No obvious precipitant | 2 | CS 20 mg, Pyd 60 mg q6h, tac 3 mg, IVMP, IVIG | |
Case 5 | 69 | Female | 1 year | Musk-Ab | Normal | PE、PMV、Tr | Bulbar, respiratory and limb muscles | Aspiration pneumonia | 1 | No |