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Table 2 Univariate and multivariate regression analysis of characteristics associated with ENDi in the training cohort

From: Association of blood pressure parameters on early neurological deterioration in patients with mild stroke and large vessel occlusion following medical management

Variables

Univariate

Multivariate

OR (95% CI)

P

OR (95% CI)

P

SBP at admission

 Quartile 1

Ref

 

Ref

 

 Quartile 2

0.89 (0.51–1.29)

0.469

0.91 (0.68–1.17)

0.799

 Quartile 3

1.25 (0.97–2.24)

0.056

1.17 (0.84–1.46)

0.120

 Quartile 4

3.27 (1.85–6.52)

< 0.001

2.47 (1.47–4.29)

< 0.001

SBP variability

 Quartile 1

Ref

 

Ref

 

 Quartile 2

1.60 (0.80–4.20)

0.195

1.10 (0.77–2.37)

0.420

 Quartile 3

2.60 (0.91–5.17)

0.095

1.47 (1.07–3.37)

0.012

 Quartile 4

3.47 (1.57–7.14)

< 0.001

2.57 (1.34–5.18)

< 0.001

Tmax > 6 s volume

 Quartile 1

Ref

 

Ref

 

 Quartile 2

1.50 (0.76–2.90)

0.140

1.09 (0.88–1.89)

0.417

 Quartile 3

2.69 (1.26–3.90)

0.001

1.47 (0.98–1.71)

0.068

 Quartile 4

3.50 (1.76–7.90)

< 0.001

2.09 (1.28–5.89)

0.001

Occlusion site

 M2 MCA

Ref

 

Ref

 

 M1 MCA

1.41 (0.92–1.96)

0.141

1.21 (0.89–1.64)

0.271

 ICA

1.56 (0.79–2.21)

0.374

1.17 (0.91–1.44)

0.192

 Vertebrobasilar

4.07 (1.96–9.19)

< 0.001

3.19 (1.76–6.74)

< 0.001

  1. Abbreviations: ENDi Early neurological deterioration of ischemic origin, OR Odds ratio, CI Confidence interval, SBP Systolic blood pressure, MCA Middle cerebral artery, ICA Internal carotid artery