Clinical and imaging risk factors for early neurological deterioration and long-term neurological disability in patients with single subcortical small infarction

Table 3 ROC curve parameters for predictors of unfavorable outcomes at follow-up and early neurological deterioration

outcome	Variables	AUC	95%CI	P value	cut-off value	Sensitivity	Specificity	DeLong test
mRS>2	Age	0.746	0.654–0.838	< 0.001	67.5	0.655	0.792	0.0001^*
	NIHSS	0.804	0.723–0.885	< 0.001	3.5	0.862	0.65	0.0018^*
	Lacune number	0.675	0.564–0.786	0.002	1.5	0.552	0.75	< 0.0001^*
	Cerebral atrophy	0.747	0.643–0.85	< 0.001	0.5	0.724	0.708	< 0.0001^*
	Predictive mode 1	0.926	0.889–0.964	< 0.001	-	0.897	0.815	-
END	NIHSS	0.833	0.754–0.911	< 0.001	4.5	0.833	0.76	0.9094^
	NHR	0.664	0.524–0.804	0.02	5.28	0.667	0.657	0.0026^
	Predictive mode 2	0.836	0.744–0.927	< 0.001	-	0.722	0.875	-

*Compared with prediction model 1; ^compared with prediction model 2
AUC Area Under the Curve, NIHSS national institutes of health stroke scale, MCHC Mean Hemoglobin Concentration, NHR neutrophil to high-density lipoprotein cholesterol ratio

ISSN: 1471-2377