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Table 1 Baseline characteristics of participants

From: Asymmetric U-shaped relationship between blood glucose and white matter lesions: results of a cross-sectional study

Covariates

Total

Baseline blood glucose (mg/dl)

P-value

< 95

95–100

101–107

> 107

(n = 1904)

1(n = 457)

2(n = 494)

3(n = 434)

4(n = 519)

Age(years), n(%)

     

< 0.001

 20–59

1050(55.1)

282(61.7)

296(59.9)

246(56.7)

226(43.5)

 

 ≥60

854(44.9)

175(38.3)

198(40.1)

188(43.3)

293(56.5)

 

Gender, n(%)

     

< 0.001

 Female

988(51.9)

153(33.5)

233(47.2)

261(60.1)

341(65.7)

 

 Male

916(48.1)

304(66.5)

261(52.8)

173(39.9)

178(34.3)

 

PS

1.1 ± 2.0

0.8 ± 1.7

0.9 ± 1.8

0.9 ± 1.8

1.7 ± 2.4

< 0.001

LDL(mg/dl)

120.9 ± 30.4

118.3 ± 29.0

120.6 ± 29.8

123.2 ± 31.7

121.4 ± 31.1

0.107

HDL(mg/dl)

61.1 ± 15.4

65.0 ± 15.8

62.7 ± 15.9

60.8 ± 14.8

56.5 ± 13.8

< 0.001

TG(mg/dl)

111.8 ± 99.8

89.1 ± 54.3

95.4 ± 53.0

119.9 ± 140.9

140.7 ± 114.5

< 0.001

Plaque, M(IQR)

0.0(0.0,1.0)

0.0(0.0,1.0)

0.0(0.0,1.0)

0.0(0.0,1.0)

0.0(0.0,2.0)

< 0.001

LH

2.1 ± 0.8

1.9 ± 0.7

2.1 ± 0.7

2.2 ± 0.8

2.3 ± 0.8

< 0.001

HbA1c(%)

5.8 ± 0.6

5.5 ± 0.3

5.6 ± 0.3

5.7 ± 0.3

6.3 ± 0.9

< 0.001

BMI(kg/m2)

23.2 ± 3.4

21.8 ± 3.0

22.6 ± 2.9

23.4 ± 3.2

24.7 ± 3.7

< 0.001

MAP(mmHg)

90.5 ± 13.3

86.4 ± 12.7

89.3 ± 12.6

91.7 ± 13.5

94.4 ± 13.2

< 0.001

Smoking, n(%)

     

0.741

 No

1568(82.4)

382(83.6)

407(82.4)

359(82.7)

420(80.9)

 

 Yes

336(17.6)

75(16.4)

87(17.6)

75(17.3)

99(19.1)

 

Amount of drink, n(%)

     

< 0.001

 < 180ML/day

1224(64.3)

331(72.4)

334(67.6)

257(59.2)

302(58.2)

 

 180ML-360ML/day

467(24.5)

86(18.8)

110(22.3)

124(28.6)

147(28.3)

 

 360ML-540ML/day

158(8.3)

29(6.3)

38(7.7)

38(8.8)

53(10.2)

 

 > 540ML/day

55(2.9)

11(2.4)

12(2.4)

15(3.5)

17(3.3)

 

Cholesterol-lowering drugs, n(%)

     

< 0.001

 No

1589(83.5)

408(89.3)

438(88.7)

367(84.6)

376(72.4)

 

 Yes

315(16.5)

49(10.7)

56(11.3)

67(15.4)

143(27.6)

 

Drink habit, n(%)

     

< 0.001

 Rarely drink

796(41.8)

218(47.7)

231(46.8)

160(36.9)

187(36)

 

 Sometimes

565(29.7)

154(33.7)

137(27.7)

130(30)

144(27.7)

 

 Everyday

543(28.5)

85(18.6)

126(25.5)

144(33.2)

188(36.2)

 

Insulin, n(%)

     

< 0.001

 No

1765(92.7)

454(99.3)

489(99)

423(97.5)

399(76.9)

 

 Yes

139(7.3)

3(0.7)

5(1)

11(2.5)

120(23.1)

 

Metabolic syndrome, n(%)

     

< 0.001

 No

1429(75.1)

413(90.4)

418(84.6)

321(74)

277(53.4)

 

 Reserve

196(10.3)

33(7.2)

49(9.9)

69(15.9)

45(8.7)

 

 Yes

279(14.7)

11(2.4)

27(5.5)

44(10.1)

197(38)

 

Antihypertensive drugs, n(%)

     

< 0.001

 No

1442(75.7)

391(85.6)

407(82.4)

334(77)

310(59.7)

 

 Yes

462(24.3)

66(14.4)

87(17.6)

100(23)

209(40.3)

 
  1. Abbreviations: IQR, interquartile range; SD, standard deviation; PS, carotid plaque score; LDH, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; TG, triglyceride; HbA1c, hemoglobin A1c; LH, ratio of LDL to HDL; BMI, body mass index; MAP, mean arterial pressure; Plaque N, plaque number
  2. a Variables are presented as mean ± SD, median (IQR) or n (%)