Fig. 1
From: Leukemia and risk of stroke: a Mendelian randomization analysis

Assumptions of a Mendelian randomization analysis for leukemia subtypes and stroke risk are depicted in the diagram. Broken lines symbolize potential pleiotropic or direct causal effects between variables that could breach Mendelian randomization assumptions. ALL = Acute Lymphoblastic Leukemia, AML = Acute Myeloid Leukemia; CLL = Chronic Lymphocytic Leukemia, CML = Chronic Myeloid Leukemia; IS = Ischemia stroke; ICH = Intracerebral hemorrhage