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Table 2 Demographic and clinical differences between EDSS < 4 and EDSS ≥ 4 in patients with acute NMOSD

From: Acute neuromyelitis optica spectrum disorder patients’ clinical analysis of disability-related biomarkers

Clinical characteristics

EDSS<4

EDSS ≥ 4

P-value

N = 21

N = 20

Sex, (N,%)

Male

Female

Male

Female

> 0.999

13(61.90%)

8(38.10%)

12(60.00%)

8(40.00%)

Age, y (mean ± SD)

33.33 ± 672

37.44 ± 15.545

0.453

AQP4-IgG + of patients(n,%)

7(33.33%)

8(40%)

0.906

Focus:

 

0.172

Optic neuritis(n,%)

4(19.04%)

2(10.00%)

 

Acute myelitis(n,%)

16(76.19%)

13(65.00%)

Mix attacks(n,%)

1(4.77%)

5(25.00%)

QAlb (M, IQR)

4.74 (4.04, 5.24)

7.17 (5.20, 9.68)

0.005

QIgG (M, IQR)

2.43 (1.95, 2.74)

3.97 (2.68, 5.50)

0.002

QIgA (M, IQR)

1.41 (1.07, 1.60)

1.99 (1.29, 3.23)

0.016

QIgM (M, IQR)

0.28 (0.18, 0.50)

0.78 (0.49, 1.12)

0.002

CSFIgG index (M, IQR)

0.49 (0.41, 0.54)

0.55 (0.50, 0.60)

0.072

NLR(M, IQR)

1.71 (1.23, 2.86)

2.25 (1.59, 3.84)

0.190

MLR(M, IQR)

1.19 (0.26, 1.54)

0.29 (0.21, 1.41)

0.306

PLR(M, IQR)

101.02 (94.21, 116.45)

157.93 (133.70, 230.28)

< 0.001