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Table 1 Patients demographics and baseline disease characteristics

From: Primary central nervous system tumors in patients with multiple sclerosis

Variable

Patients with ptCNS (n = 36)

Patients without ptCNS (n = 2244)

p-value

Age (mean ± SD)

 At MS onset

 At tumor diagnosis (mean ± SD)

31.47 ± 9.10

45.47 ± 8.08

29.18 ± 8.96

--

0.13

Sex (n,%)

 Male

 Female

1 (2.8%)

35 (97.2%)

309 (13.8%)

1935 (86.2%)

0.056

Type of MS (n,%)

 RRMS

 SPMS

 PPMS

35 (97.2%)

1 (2.8%)

0 (0)

1980 (88.20%)

188 (8.40%)

76 (3.40%)

0.23

Type of Medication (n,%)

 INF beta-1a

 INF beta-1b

 Rituximab

 Glatiramer Acetate

 Dimethyl Fumarate

 Fingolimod

 Teriflunomide

22 (61.1%)

5 (13.9%)

3 (8.3%)

1 (2.8%)

3 (8.3%)

1 (2.8%)

1 (2.8%)

351 (18.3%)

239 (12.4%)

344 (17.9%)

63 (3.3%)

514 (26.7%)

209 (10.9%)

202 (10.5%)

< 0.001

  1. IFN: Interferon, MS: multiple sclerosis, PPMS: Primary Progressive MS, ptCNS: Primary tumor of the CNS, RRMS: Relapsing-remitting MS, SD: Standard deviation, SPMS: Secondary Progressive MS