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Table 1 Comparison of baseline characteristics between PI and non-PI groups

From: Imaging predictors of progressive infarction in patients with anterior circulation small subcortical infarction

Variable

PI

(n = 121)

Non-PI

(n = 517)

P

Demographic characteristics

   

Age (y), median (IQR)

65 (55, 71)

64 (55, 72)

0.464

Male, n (%)

78 (64.5%)

347 (67.1%)

0.577

Clinical data

   

Hypertension, n (%)

110 (90.9%)

461 (89.2%)

0.742

Diabetes, n (%)

38 (31.4%)

161 (31.1%)

0.955

History of stroke, n (%)

  

0.964

 None

104 (85.9%)

445 (86.1%)

 

 Ischemic

15 (12.4%)

62 (11.9%)

 

 Hemorrhagic

2 (1.7%)

10 (1.9%)

 

Initial NIHSS score, median (IQR)

4 (2, 6)

3 (2, 5)

0.003*

Discharge NIHSS score, median (IQR)

4 (2, 6)

2 (1, 3)

< 0.001*

Laboratory data

   

WBC (10*9/L), median (IQR)

6.60 (5.22, 7.75)

6.45 (5.21, 7.56)

0.476

RBC (g/L), mean ± SD

4.46 ± 0.47

4.47 ± 0.54

0.828

HGB (g/L), median (IQR)

136 (127, 145)

135 (126, 145)

0.637

PLT (10*9/L), median (IQR)

200 (159.5, 238)

202 (170, 242)

0.454

BUN (mmol/L), median (IQR)

4.5 (3.7, 5.5)

4.8 (3.80, 5.6)

0.217

Creatinine (umol/L), median (IQR)

71.2 (56.65, 83.6)

74.5 (61, 88.05)

0.120

Uric acid (mmol/L), median (IQR)

344.5 (282.05, 418.0)

336 (279.85, 399.65)

0.207

Fasting glucose (mg/dL), median (IQR)

104.34 (89.92, 131.18)

98.57 (85.78, 128.57)

0.080

TC (mg/dL), median (IQR)

191.42 (171.31, 225.45)

183.3 (155.84, 205.92)

0.002*

TG (mg/dL), median (IQR)

150.62 (105.87, 196.25)

117.84 (87.71, 171.88)

< 0.001*

HDL-c (mg/dL), median (IQR)

43.7 (35.38, 50.47)

44.08 (36.74, 52.2)

0.332

LDL-c (mg/dL), median (IQR)

118.72 (98.61, 144.24)

110.6 (88.55, 130.31)

0.003*

Fibrinogen (g/L), median (IQR)

2.89 (2.52, 3.38)

2.89 (2.51, 3.33)

0.638

D-dimer (mg/L), median (IQR)

0.25 (0.14, 0.48)

0.28 (0.15, 0.48)

0.217

Imaging date

   

Diameter of infarcts (mm), median (IQR)

15.6 (12.02, 21.12)

14.28 (10.16, 19.53)

0.052

Diameter of infarcts ≥ 15 mm, n (%)

64 (52.9%)

239 (46.2%)

0.190

Diameter of infarcts ≥ 10 mm, n (%)

106 (87.6%)

398 (76.9%)

0.009*

Axial slices of infarcts, mean ± SD

3.25 ± 1.21

2.8 ± 1.33

0.001*

Axial slices of infarcts ≥ 3, n (%)

88 (72.7%)

271 (52.4%)

< 0.001*

BAD1

79 (65.3%)

252 (48.7%)

0.001*

BAD2

57 (47.1%)

199 (38.5%)

0.082

  1. PI: Progressive Infarction; NIHSS: National Institute of Health Stroke Scale; WBC: White Blood Cell; RBC: Red Blood Cell; HGB: Hemoglobin; PLT: Platelet; BUN: Blood Urea Nitrogen; TC: Total Cholesterol; TG: Triglyceride; HDL-c: High Density Lipoprotein cholesterol; LDL-c: Low Density Lipoprotein cholesterol; IQR: Interquartile Range. SD: Standard Deviation. *p < 0.05. BAD [1]: Branch atheromatous disease defined as axial slices of infarcts ≥ 3 and the infarct diameter ≥ 10 mm. BAD [2]: Branch atheromatous disease defined as axial slices of infarcts ≥ 3 and the infarct diameter ≥ 15 mm
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BMC Neurology

ISSN: 1471-2377

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