Table 4 Comparison of characteristics of Parkinson’s patients with different course of disease M(P25 ∼ P75)/ \(\:\stackrel{-}{\varvec{x}}\pm\:\varvec{s}\) / n(%)

Age: ≥65 years

69(46.9)

39(47.6)

0.008

0.928

Gender: male

62(42.2)

51(62.2)

8.439

0.004

BMI

 Normal

44(29.9)

24(29.3)

0.084

0.959

 Wasting

6(4.1)

4(4.9)

 Overweight or obesity

97(66.0)

54(65.9)

SBP (mmHg)

130.00(120.00 ∼ 137.00)

130.00(121.00 ∼ 137.25)

-0.097

0.923

DBP (mmHg)

76.00(70.00 ∼ 83.00)

75.00(68.75 ∼ 80.25)

-1.302

0.193

Heart rate (beats/min)

75(69.00 ∼ 83.00)

77.00(68.00 ∼ 85.00)

-0.712

0.477

Alcohol: yes

18(12.2)

8(9.8)

0.324

0.569

Smoking: yes

18(12.2)

11(13.4)

0.065

0.799

Hypertension: yes

47(32.0)

27(32.9)

0.022

0.882

Diabetes mellitus: yes

19(12.9)

8(9.8)

0.508

0.476

Hyperlipidemia: yes

4(2.7)

1(1.2)

0.556

0.456

Kidney disease: yes

0(0.0)

1(1.2)

1.801

0.180

Atrial fibrillation: yes

5(3.4)

3(3.7)

0.010

0.919

Cystatin C

0.95 ± 0.29

1.05 ± 0.35

-2.197

0.029

Urea

5.01(4.23 ∼ 6.17)

5.54(4.44 ∼ 6.46)

-2.316

0.021

Uric acid

284.09 ± 77.82

288.99 ± 85.93

-0.438

0.662

Creatinine

66.00(56.00 ∼ 76.00)

69.00(58.00 ∼ 78.00)

-0.932

0.352

H-Y staging (≥ 3)

52(35.6)

39(48.8)

3.706

0.054