Quickest way to less headache days: an operational research model and its implementation for chronic migraine

BMC Neurology

Table 3 Calculations of indexes for second iteration based on input data

	σ_i1	σ_i2	σ_i3	\(\sigma ({t}_{i}^{*})\)
OnabotulinumtoxinA lower bound	0	0.03376108562	0.01701839441	0.03376108562
OnabotulinumtoxinA upper bound	0	0.03782568807	0.01988201633	0.03782568807
Topiramate lower bound	0	0.011710568	0.00739479	0.011710568
Topiramate upper bound	0	0.015871804	0.01012158667	0.01587180365
Erenumab		0.071686204	0.09119278779	0.091192788

Note: Input adjusted to ensure probabilities are increasing over time. σ_ik represents the index for each medication at specific time k for drug i

ISSN: 1471-2377