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Table 2 Comparison of the participants’ baseline inflammatory markers and clinical outcomes

From: Effects of very early exercise on inflammatory markers and clinical outcomes in patients with ischaemic stroke- a randomized controlled trial

Variable

Total (N = 48)

Mean ± SD/Median (IQR)

VEEG (n = 24)

Mean ± SD/Median (IQR)

UCG (n = 24)

Mean ± SD/Median (IQR)

t/U

p-value

Inflammatory markers

 Interleukin-6 (pg/ml)

6.34 ± 3.15

6.39 ± 3.34

6.28 ± 3.00

0.123a

0.903

 Fibrinogen (mg/dl)

417.3 ± 76.3

424.5 ± 79.0

410.0 ± 74.5

0.650a

0.519

 Leucocytes (× 103/uL)

8.48 ± 3.88

7.60 ± 4.23

9.36 ± 3.36

1.591a

0.118

 Neutrophils (× 103/uL)

5.69 ± 3.68

5.38 ± 3.94

5.99 ± 3.45

0.575a

0.568

 Lymphocytes (× 103/uL)

2.87 ± 2.21

3.02 ± 2.78

2.71 ± 1.51

0.474a

0.638

 Monocytes (× 103/uL)

0.67 ± 0.34

0.63 ± 0.32

0.72 ± 0.35

0.968a

0.338

Clinical outcomes

 Motor impairment (SMSNIHSS)

4.50 (4.0–5.0)

5.0 (4.0–5.0)

4.0 (4.0–5.0)

248.0b

0.360

 Physical disability (mRS)

4.0 (4.0–5.0)

5.0 (4.0–5.0)

4.0 (3.0–5.0)

215.5b

0.105

 Functional independence (MBI)

65.0 (44.0–72.7)

66.5 (46.2–76.5)

60.0 (33.0–72.5)

250.0b

0.433

 Depression (HADS-D)

9.0 (7.0–12.0)

8.5 (7.0–12.0)

9.0 (7.2–11.7)

275.5b

0.796

 Anxiety (HADS-A)

10.0 (7.0–12.0)

9.5 (6.2–11)

10.0 (7.0–12.0)

246.0b

0.383

 Cognition (MoCA)

15.0 (10.2–19.7)

14.0 (9.2–21.0)

16.0 (11.2–19.7)

278.0b

0.836

  1. at-test, bMann–Whitney U test, IQR interquartile range, SD standard deviation, SMSNIHSS Supplemental Motor Scale National Institute of Health Stroke Scale, mRS modified Ranking Scale, MBI Modified Barthel Index, HADS-D Hospital Anxiety and Depression Scale-Depression Sub-scale, HADS-A Hospital Anxiety and Depression Scale-Anxiety Sub-scale, MoCA Montreal Cognitive Assessment, VEEG very early exercise group, UCG usual care group