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Table 2 GAP-43 and [18 F] AV45 alterations across diagnostic groups

From: Growth associated protein 43 (GAP-43) predicts brain amyloidosis in Alzheimer’s dementia continuum: an [18 F] AV-45 study

 

CN

(n = 77)

MCI

(n = 111)

AD

(n = 38)

Comparison

P value *

P value

GAP-43 (pg/Ml)

5209.87 ± 2872.67

5304.65 ± 2763.97

8073.61 ± 3680.66

CN vs. MCI

1.00

< 0.001a

CN vs. AD

< 0.001

MCI vs. AD

< 0.001

[18F] AV45

1.14 ± 0.26

1.19 ± 0.20

1.42 ± 0.23

CN vs. MCI

0.500

< 0.001a

CN vs. AD

< 0.001

MCI vs. AD

< 0.001

  1. Abbreviations: CN: cognitively normal; MCI: mild cognitive impairment; AD: Alzheimer’s disease; GAP-43: Growth Associated Protien-43; a ANOVA test; * Significance values have been adjusted by the Bonferroni correction for multiple tests
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BMC Neurology

ISSN: 1471-2377

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