BMC Neurology

Table 5 Linear regression analysis of [¹⁸F] AV45 and the predictive effect of GAP-43 across diagnostic groups

From: Growth associated protein 43 (GAP-43) predicts brain amyloidosis in Alzheimer’s dementia continuum: an [¹⁸ F] AV-45 study

	CN (n = 77)			MCI (n = 111)			AD (n = 38)
	Standardized β	t value	P value	Standardized β	t value	P value	Standardized β	t value	P value
GAP-43	0.264	2.591	0.012	0.220	2.319	0.022	0.381	2.334	0.026
MMSE	-0.126	-1.247	0.217	-0.306	-3.279	0.001	-0.289	-1.694	0.100
Age	0.371	3.661	< 0.001	0.016	0.166	0.869	-0.104	-0.565	0.576
Gender	0.153	1.454	0.150	-0.053	-0.549	0.584	0.075	0.415	0.681
Education	-0.170	-1.623	0.109	0.052	0.514	0.608	0.177	1.074	0.291
Adjusted R²	0.235			0.103			0.064
Model p value	< 0.001			0.005			0.216

Abbreviations: CN: cognitively normal; MCI: mild cognitive impairment; AD: Alzheimer’s disease; MMSE: Mini-Mental State Examination; GAP-43: Growth Associated Protien-43

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ISSN: 1471-2377

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