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Table 6 Diagnostic performance of CSF biomarkers

From: Growth associated protein 43 (GAP-43) predicts brain amyloidosis in Alzheimer’s dementia continuum: an [18 F] AV-45 study

 

CN vs. MCI

 

CN vs. AD

 

MCI vs. AD

 

AUC

P value

AUC

P value

AUC

P value

GAP-43

0.514

0.043

0.737

< 0.001

0.736

< 0.001

Aβ42

0.414

0.042

0.168

< 0.001

0.233

< 0.001

T-tau

0.567

0.043

0.839

< 0.001

0.802

< 0.001

P-tau

0.566

0.043

0.843

< 0.001

0.805

< 0.001

  1. Abbreviations: CN: cognitively normal; MCI: mild cognitive impairment; AD: Alzheimer’s disease; T-tau: total tau; P-tau: phosphorylated tau; Aβ: amyloid-βGAP-43: Growth Associated Protien-43