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Fig. 3 | BMC Neurology

Fig. 3

From: Intrathecal interleukin-6 levels are associated with progressive disease and clinical severity in multiple sclerosis

Fig. 3

Intrathecal IL-6 is increased in PPMS. IL-6 levels in CSF of HCs vs. RRMS and PPMS measured with Ella®. (A) IL-6 levels were significantly higher in PPMS vs. HCs (p = 0.0428). Statistical significance was determined using the Mann-Whitney test. * p < 0.5. (B) Receiver operating characteristic (ROC) analysis demonstrated the capacity of IL-6 levels to distinguish between RRMS and PPMS with an area under the curve (AUC) of 0.7060, and statistical significance (p = 0.0139)

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