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Table 1 Characteristics of patients in early window and late window

From: Late time window endovascular treatment for acute ischemic stroke: rethinking the role of simplified imaging

Variable

Early time window

(n = 111)

Late time window

(n = 131)

P values

Clinical baseline data

   

 Age, median (IQR), y

71(60–79)

68(56–75)

0.036

 Male, n (%)

69(62.2)

81(61.8)

0.958

 NIHSS score, median (IQR)

17(14–21)

15(11–19)

0.008

 ASPECTS, median (IQR)

9(8–10)

8(7–10)

0.008

Risk factors

   

 Hypertension, n (%)

77(69.4)

84(64.1)

0.389

 Diabetes, n (%)

22(19.8)

21(16)

0.442

 Atrial fibrillation, n (%)

62(55.9)

43(32.8)

0.001

 Smoking, n (%)

28(25.2)

26(19.8)

0.317

Baseline measurements

   

 SBP, median (IQR), mm Hg

152(132–170)

153(135–170)

0.690

 Platelet, mean (IQR), 109/L

172(143–205)

182(143–212)

0.330

 Glucose, median (IQR), mmol/L

6.8(6.2–8.6)

7.1(6.1–8.3)

0.937

Occlusion site, n (%)

  

0.249

 ICA

38(34.2)

54(41.2)

 

 MCA-M1

68(61.3)

75(57.3)

 

 MCA-M2

5(4.5)

2(1.5)

 

Stroke cause, n (%)

  

0.002

 LAA

32(29.1)

66(51.6)

 

 Cardioembolic

60(54.5)

47(36.7)

 

 Others

18(16.4)

15(11.7)

 

Procedural data

   

 Intravenous thrombolysis, n (%)

65(58.6)

34(26)

0.001

 OTP, median (IQR), min

240(167–293)

590(457–836)

0.001

 OTR, median (IQR), min

299(227–370)

647(529–909)

0.001

 eTICI, 2b or 3, n (%)

107(96.4)

119(90.8)

0.083

Outcome

   

 mRS score 0–2 (%)

56(50.5)

55(42)

0.188

 mRS score 6 (%)

20(18)

13(9.9)

0.067

 ICH (%)

29(26.1)

27(20.6)

0.311

  1. IQR, interquartile range; NIHSS, National Institute of Health Stroke Scale; ASPECTS, Alberta Stroke Program Early Computed Tomography Score; SBP, systolic blood pressure; ICA, Internal Carotid Artery; MCA-M1, Middle Cerebral Artery-M1 Segment; LAA, large-artery atherosclerosis; eTICI, expanded Thrombolysis in Cerebral Infarction; OTP, symptoms onset to groin puncture time; OTR, symptoms onset to recanalization time; mRS, modified Rankin Scale; ICH, intracranial hemorrhage