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Table 5 Value of cystatin C and other clinical scores for predicting mortality and unfavorable functional outcome of included aSAH patients

From: Association between initial serum cystatin C level and prognosis of aneurysmal subarachnoid hemorrhage

 Factors

AUC

95%Cl

Sensitivity

Specificity

Cut off value

Predicting mortality

 Cystatin C

0.718

0.646–0.789

0.696

0.645

0.76

 GCS

0.800

0.730–0.870

0.689

0.804

13

 Hunt-Hess

0.786

0.719–0.853

0.821

0.629

3

 WFNS

0.791

0.722–0.860

0.804

0.693

4

 mFisher

0.692

0.611–0.773

0.625

0.729

3

 GCS + cystatin C

0.852

0.801–0.902

0.911

0.765

0.1384

 Predictive model 1

0.899

0.858–0.939

0.804

0.757

0.1251

Predicting unfavorable functional outcome

 Cystatin C

0.669

0.609–0.730

0.490

0.801

0.79

 GCS

0.749

0.694–0.805

0.833

0.642

13

 Hunt-Hess

0.735

0.678–0.791

0.662

0.750

3

 WFNS

0.750

0.694–0.805

0.642

0.84

4

 mFisher

0.640

0.578–0.702

0.477

0.795

3

 Predictive model 2

0.872

0.833–0.911

0.728

0.859

0.5563

  1. The model 1 composed of GCS, mFisher, cystatin C and delayed cerebral ischemia
  2. The model 2 composed of age, GCS, delayed cerebral ischemia and pneumonia
  3. AUC area under receiver operating characteristic curve, GCS Glasgow Coma Scale, WFNS World Federation Neurosurgery Society