Analysis of the glymphatic system function in high-grade glioma patients using diffusion tensor imaging along perivascular spaces

Table 2 Comparison between ALPS indices by different tumor grades, tumour location, tumour and oedema volume

parametric	Glioma group (n = 50)		Control group (n = 50)	^#P-value	*P-value	^&P-value
parametric	Ipsilateral ALPS index	Contralateral ALPS index	Control group (n = 50)	^#P-value	*P-value	^&P-value
Mean ALPS	1.36 ± 0.25	1.54 ± 0.19	1.73 ± 0.21	< 0.001	< 0.001	< 0.001
Tumor grade
3	1.45 ± 0.26	1.62 ± 0.21		< 0.001	0.068	0.031
4	1.30 ± 0.23	1.50 ± 0.18		< 0.001	< 0.001	< 0.001
Tumor volume
Large	1.38 ± 0.26	1.49 ± 0.18		< 0.001	< 0.001	0.079
Small	1.33 ± 0.25	1.59 ± 0.20		< 0.001	0.014	< 0.001
Edema volume
Large	1.29 ± 0.25	1.52 ± 0.21		< 0.001	< 0.001	< 0.001
Small	1.42 ± 0.24	1.56 ± 0.19		< 0.001	0.001	0.24
Tumor location
left hemisphere	1.35 ± 0.26	1.53 ± 0.21		< 0.001	< 0.001	0.004
right hemisphere	1.36 ± 0.24	1.55 ± 0.19		< 0.001	0.001	0.004

Note: # indicates comparison of ALPS index on the affected side of the glioma group with the control group; * indicates comparison of ALPS index on the contralateral side of the glioma group with the control group; & indicates comparison of ALPS index on the contralateral side of the glioma group with the affected side

ISSN: 1471-2377