Fig. 2

Blood metabolite measures. Control subjects: FBG (A), TC (B) and uric acid (C). DM2 subjects: FBG (D), TC (E), urea (F), HDL (G), LDL (H), and creatinine (I). Green boxes show normal levels in blood. N = 12–37 subjects per group, mean ± SEM. Cognitive impairment: CI*, p ≤ 0.05. Factor interaction effect: sex and cognitive impairment: S × CI*, p ≤ 0.05. Differences between two counterparts, sex: $$p ≤ 0.01; Cognitive impairment: * p ≤ 0.05