Cerebral microbleeds: prevalence and relationship to clinical features in cognitive impairment with lewy body disease

Table 3 Associations between the presence of CMBs and clinical core features in all cases

Clinical core feature		Crude					Model 1					Model 2
Clinical core feature		B	SE	OR	95%CI	P	B	SE	OR	95%CI	P	B	SE	OR	95%CI	P
Visual hallucinations	Constant	0.772	0.080	2.165		< 0.001	-1.899	0.678	0.150		0.005	-1.775	0.695	0.170		0.011
Visual hallucinations	CMB	0.234	0.179	1.264	0.890 ~ 1.796	0.191	0.654	0.225	1.924	1.238 ~ 2.990	0.004	0.468	0.232	1.597	1.014 ~ 2.517	0.044
Fluctuating cognition	Constant	-0.068	0.074	0.934		0.355	-1.314	0.623	0.269		0.035	-1.17	0.63	0.310		0.063
Fluctuating cognition	CMB	0.478	0.163	1.613	1.172 ~ 2.220	0.003	0.653	0.201	1.921	1.296 ~ 2.846	0.001	0.535	0.206	1.707	1.140 ~ 2.556	0.009
Parkinsonism	Constant	1.186	0.087	3.275		< 0.001	5.951	0.820	384.224		< 0.001	6.017	0.825	410.189		< 0.001
Parkinsonism	CMB	-0.047	0.187	0.954	0.661 ~ 1.378	0.803	0.552	0.244	1.737	1.077 ~ 2.801	0.024	0.479	0.249	1.615	0.991 ~ 2.631	0.054
RBD	Constant	0.273	0.075	1.313		< 0.001	-1.054	0.626	0.348		0.092	-1.072	0.627	0.342		0.087
RBD	CMB	-0.029	0.161	0.971	0.708 ~ 1.333	0.858	0.148	0.199	1.160	0.786 ~ 1.713	0.455	0.177	0.203	1.193	0.802 ~ 1.776	0.384

Data for core clinical features was shown with “OR (95% CIs)” by binary logistic regressions. All analysis were performed by Crude model, Model 1 (with correction for age at last visit, sex, history of hypertension, T2DM, heart disease, stroke, and the habits of smoking and/or alcohol consumption), and Model 2 (with correction for Model 1 + scores of MTA-max and Fazekas). *p < 0.05, ** p < 0.01, *** p < 0.001
CMBs, cerebral microbleeds; ORs, odd ratios; 95% CIs, 95% confidential intervals; RBD, rapid eye movement sleep behavior disorder

ISSN: 1471-2377