Table 4 Two-step MR results for P2X6 as a mediator variable for PD and gastric cancer
From: Causal relationship between Parkinson’s disease and gastric cancer: a Mendelian randomization study
Nsnp | β | SE | P value | |
|---|---|---|---|---|
PD as the exposure and P2X6 as the outcome | 17 | 0.100569 | 0.047194 | 0.033094 |
P2X6 as the exposure and gastric cancer as the outcome | 1 | − 0.191464 | 0.096028 | 0.046171 |
Mediating effect | Direct effect | |||
PD as the exposure, gastric cancer as the outcome, and P2X6 as the mediator | − 0.0193 | − 0.04647 |