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Table 3 Univariable and multivariable logistic regression analyses of risk factors for ICH

From: The hypoperfusion volume has a strong predictive value for hemorrhagic transformation in acute ischemic stroke patients with anterior circulation occlusion after endovascular thrombectomy

Parameter

Univariable analysis

OR (95% CI)

P value

Multivariable analysis

OR (95% CI)

P value

Age

0.990 (0.958–1.022)

0.533

  

Female

0.488 (0.208–1.144)

0.099

  

Baseline NIHSS

1.091 (1.014–1.173)

0.019*

1.081 (1.003–1.165)

0.041*

Baseline ASPECTS

0.692 (0.492–0.971)

0.033*

  

Medical history

    

 Hypertension

0.504 (0.224–1.132)

0.097

  

 Diabetes

0.488 (0.208–1.144)

0.099

  

 Hyperlipidemia

0.358 (0.142–0.906)

0.030*

  

 Atrial fibrillation

1.517 (0.603–3.812)

0.376

  

Smoking

1.420 (0.515–3.916)

0.498

  

Obesity

0.804 (0.329–1.961)

0.631

  

Intravenous alteplase treatment

1.221 (0.426–3.499)

0.711

  

Systolic blood pressure

0.994 (0.976–1.013)

0.553

  

Diastolic blood pressure

0.994 (0.964–1.024)

0.688

  

Onset to door

1.000 (1.000–1.000)

0.695

  

Onset to recanalization

1.000 (1.000–1.000)

0.686

  

Number of passes

1.306 (0.868–1.964)

0.200

  

Laboratory testing

    

 Platelet count

1.003 (0.997–1.009)

0.331

  

 INR

0.385 (0.014–10.806)

0.575

  

 APTT

0.969 (0.910–1.031)

0.317

  

 D-dimer

0.939 (0.795–1.110)

0.463

  

 ALT

1.004 (0.970–1.039)

0.827

  

 AST

1.014 (0.984–1.045)

0.363

  

 HbA1C

0.755 (0.578–1.068)

0.128

  

 Infarct core volume

1.016 (0.997–1.036)

0.101

  

 Hypoperfusion volume

1.007 (1.001–1.012)

0.019 *

1.006 (1.001–1.012)

0.033*

  1. Abbreviations: NIHSS, National Institutes of Health stroke scale; ASPECTS, Alberta Stroke Program Early CT Score; ICH, Intracerebral Hemorrhage; INR, International Standard Ratio; APTT, Activated Partial Thromboplastin Time; ALT, Alanine Transaminase; AST, Aspartate Transaminase; HbA1C, Hemoglobin A1c; IQR, Median and Interquartile Range; OR, Odds Ratio; CI, Confidence Interval
  2. *P < 0.05