Table 3 MR analyses by IVW approach and sensitivity analyses of potential mediators on AD
Classification | nSNP | IVW | Heterogeneilty | Pleiotropy | MR-PRESSO | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Exposure | Outcome | SE | P value | OR (95%CI) | Q | P value | Egger intercept | SE | P value | Global Test P-value | |
CD28+ CD45RA− CD8br AC | AD | 17 | 0.006 | 0.005 | 0.983 (0.971–0.995) | 15.148 | 0.514 | 0.002 | 0.004 | 0.591 | 0.579 |