Table 3 Directional horizontal Pleiotropy assessed by intercept term in MR Egger regression of the association betweensphingomyelin levels and gut microbiota abundance (P > 0.05)
Exposure | Outcome | Egger intercept | Se | P value |
|---|---|---|---|---|
Sphingomyelin levels | family Alcaligenaceae | -0.006 | 0.004 | 0.136 |
species Ruminococcus callidus | 0.005 | 0.009 | 0.578 | |
genus Flavonifractor | 0.008 | 0.010 | 0.404 | |
genus Streptococcus | -0.002 | 0.004 | 0.54 | |
species Haemophilus parainfluenzae | -0.008 | 0.010 | 0.432 | |
species Bacteroides caccae | 0.003 | 0.007 | 0.662 |