Table 4 MR-PRESSO analysis for the association between betweensphingomyelin levels and gut microbiota abundance. (P > 0.05)
Exposure | Outcome | MR Analysis | Causal estimate | SD | T | P-value | RSSobs | Global test P-value |
|---|---|---|---|---|---|---|---|---|
Sphingomyelin levels | family Alcaligenaceae | MR-PRESSO | 0.106 | 0.031 | 3.462 | 0.001 | 38.591 | 0.959 |
species Ruminococcus callidus | 0.189 | 0.090 | 2.086 | 0.421 | 51.210 | 0.499 | ||
genus Flavonifractor | -0.204 | 0.961 | -2.121 | 0.039 | 51.860 | 0.503 | ||
genus Streptococcus | -0.942 | 0.038 | -2.511 | 0.015 | 57.165 | 0.437 | ||
species Haemophilus parainfluenzae | -0.249 | 0.010 | -2.490 | 0.016 | 59.648 | 0.349 | ||
species Bacteroides caccae | -0.142 | 0.067 | -2.124 | 0.038 | 60.286 | 0.303 |