Table 4 Ontological analysis of co-DEGs among COVID-19, AMI and AIS (CES)

GO:0002366

BP

leukocyte activation involved in immune response

5.53E-05

GAB2/CLEC4D/FCER1G/DYSF/CLEC4E/ANXA3/CD177/ITGAM/SEMA4 A/TLR4/CCR6

GO:0002263

BP

cell activation involved in immune response

5.53E-05

GAB2/CLEC4D/FCER1G/DYSF/CLEC4E/ANXA3/CD177/ITGAM/SEMA4 A/TLR4/CCR6

GO:0002274

BP

myeloid leukocyte activation

5.53E-05

S100 A12/TLR2/GAB2/CLEC4D/FCER1G/DYSF/ANXA3/CD177/ITGAM/TLR4

GO:0042742

BP

defense response to bacterium

0.000417022

S100 A12/TLR2/CLEC4D/FCER1G/CLEC4E/ANXA3/FPR2/FCGR1 A/SLPI/TLR4/HP

GO:0002283

BP

neutrophil activation involved in immune response

0.000487054

FCER1G/ANXA3/CD177/ITGAM

GO:0002888

BP

positive regulation of myeloid leukocyte mediated immunity

0.000505654

FCGR1 A/CD177/ARG1/ITGAM

GO:0002699

BP

positive regulation of immune effector process

0.00058543

GAB2/SLC7 A5/CD55/FCGR1 A/FFAR2/CD177/ARG1/ITGAM/TLR4

GO:0002275

BP

myeloid cell activation involved in immune response

0.000964429

GAB2/FCER1G/DYSF/ANXA3/CD177/ITGAM

GO:0002697

BP

regulation of immune effector process

0.001248229

IRAK3/GAB2/SLC7 A5/CD55/FCGR1 A/FFAR2/CD177/ARG1/ITGAM/TLR4

GO:0002886

BP

regulation of myeloid leukocyte mediated immunity

0.001248229

GAB2/FCGR1 A/CD177/ARG1/ITGAM

GO:0070820

CC

tertiary granule

3.03E-20

QPCT/CLEC4D/FCER1G/LRG1/MMP9/MGAM/CD55/MCEMP1/FPR2/SLC2 A3/SIGLEC5/TNFAIP6/TIMP2/ORM1/CD177/ITGAM/CYSTM1/TCN1/HP

GO:0042581

CC

specific granule

1.48E-14

QPCT/CLEC4D/LRG1/ANXA3/MCEMP1/FPR2/SLC2 A3/TIMP2/ORM1/CD177/ARG1/SLPI/ITGAM/TCN1/HP

GO:0070821

CC

tertiary granule membrane

2.84E-11

CLEC4D/FCER1G/MGAM/MCEMP1/FPR2/SLC2 A3/SIGLEC5/CD177/ITGAM/CYSTM1

GO:0030667

CC

secretory granule membrane

1.47E-10

TLR2/CLEC4D/FCER1G/MGAM/CD55/VNN1/MCEMP1/FPR2/SLC2 A3/MME/SIGLEC5/APLP2/CD177/ITGAM/CYSTM1

GO:0101002

CC

ficolin-1-rich granule

6.06E-10

QPCT/CLEC4D/FCER1G/LRG1/MMP9/MGAM/CD55/FPR2/SLC2 A3/SIGLEC5/TNFAIP6/TIMP2

GO:1,904,724

CC

tertiary granule lumen

2.03E-09

QPCT/LRG1/MMP9/TNFAIP6/TIMP2/ORM1/TCN1/HP

GO:0035580

CC

specific granule lumen

4.72E-09

QPCT/LRG1/TIMP2/ORM1/ARG1/SLPI/TCN1/HP

GO:0101003

CC

ficolin-1-rich granule membrane

1.37E-07

CLEC4D/FCER1G/MGAM/CD55/FPR2/SLC2 A3/SIGLEC5

GO:0034774

CC

secretory granule lumen

1.86E-07

S100 A12/S100P/QPCT/LRG1/SRGN/RNASE2/TIMP2/ORM1/ARG1/SLPI/TCN1/HP

GO:0060205

CC

cytoplasmic vesicle lumen

1.86E-07

S100 A12/S100P/QPCT/LRG1/SRGN/RNASE2/TIMP2/ORM1/ARG1/SLPI/TCN1/HP

GO:0038187

MF

pattern recognition receptor activity

0.001765518

TLR2/CLEC4D/CLEC4E/TLR4

GO:0001540

MF

amyloid-beta binding

0.005888223

TLR2/FPR2/ADRB2/ITGAM/TLR4

GO:0005543

MF

phospholipid binding

0.026361914

GAB2/DYSF/ANXA3/WDFY3/KCNJ2/MME/RPH3 A/ARHGAP26/SBF2

GO:0048306

MF

calcium-dependent protein binding

0.026361914

S100 A12/S100P/ANXA3/CD177

GO:0033218

MF

amide binding

0.026361914

TLR2/SLC7 A5/FPR2/MME/FKBP5/ADRB2/ITGAM/TLR4

GO:0140375

MF

immune receptor activity

0.026361914

IL1R2/FCER1G/FPR2/FCGR1 A/CCR6

GO:0042277

MF

peptide binding

0.030593111

TLR2/SLC7 A5/FPR2/MME/ADRB2/ITGAM/TLR4

GO:0019864

MF

IgG binding

0.036426074

FCER1G/FCGR1 A

GO:0055056

MF

D-glucose transmembrane transporter activity

0.038738178

SLC2 A14/SLC2 A3

GO:0030246

MF

carbohydrate binding

0.044172147

CLEC4D/MGAM/CLEC4E/ASGR2/SLC2 A3/SIGLEC5