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  1. To investigate the association between the presence of the HMCAS on CT prior MT and the occurrence of poor functional outcomes and sHT in LVO patients attributed to CE and LAA etiology.

    Authors: Xianghong Liu, Fang Zhang, Wenfeng Luo, Hongliang Zeng, Bin Li, Junqing Guo, Cong Zhang, Zhong Ji and Guoyong Zeng
    Citation: BMC Neurology 2025 25:63
  2. This study aimed to compare the short-term prophylactic efficacy of greater occipital nerve (GON) blockade in menstrual migraine (MM) subgroups and evaluate the long-term effects on patients’ quality of life.

    Authors: Guldeniz Cetin, Ozlem Totuk, Ozdem Erturk Cetin, Serkan Demir and Sevki Sahin
    Citation: BMC Neurology 2025 25:62
  3. Acute intermittent porphyria (AIP) is an inherited metabolic disorder that can affect the central, peripheral, and autonomic nervous systems. Therefore, its clinical presentation is diverse and may include abd...

    Authors: Jing Wang, Jiurong Chen, Ke Xu, Zhizhong Li, Gang Yu, Peng Zheng, Luo Jing, Jinzhou Feng and Xinyue Qin
    Citation: BMC Neurology 2025 25:61
  4. Neurodegenerative diseases (NDs) are conditions characterized by irreversible progressive degeneration to the nervous tissue and are usually associated with cognitive decline and functional deficits, especiall...

    Authors: Youssef A. Ismail, Youssef Haitham, Mohammad Walid, Hazim Mohamed and Youssef M. Abd El-Satar
    Citation: BMC Neurology 2025 25:60
  5. Aggregation of cohort data increases precision for studying neurodegenerative disease pathways, but efforts to combine data and expertise are often hampered by infrastructural, ethical and legal considerations...

    Authors: Julie E. Oomens, Justine E.F. Moonen, Stephanie J.B. Vos, Magdalena Beran, Pedro Mateus, Peter P. De Deyn, Wiesje M. van der Flier, Mirjam I. Geerlings, Martijn A. Huisman, M. Arfan Ikram, Miranda T. Schram, P. Eline Slagboom, W. M. Monique Verschuren, Marian Beekman, Iñigo Bermejo, Mahlet Birhanu…
    Citation: BMC Neurology 2025 25:59
  6. Acute respiratory failure is common occurrence in critical care, with varying causes, depending on case mix of the ICU. High flow nasal cannula (HFNC) is commonly utilized in both adult and pediatric populatio...

    Authors: Shalini Nair, M. Rajiv, Manoj Job and Reka Karuppasamy
    Citation: BMC Neurology 2025 25:58
  7. To explore the association between blood pressure (BP) metrics and early neurological deterioration of ischemic origin (ENDi) in patients with mild stroke and large vessel occlusion (LVO) undergoing best medical ...

    Authors: Yue Shi, Jianwen Bu, Jian-yu Liu and Shankai Liu
    Citation: BMC Neurology 2025 25:57
  8. Endoscopic surgery (ES) and small bone window craniotomy (SBWC) are commonly used methods for hematoma removal in cases of intracerebral hemorrhage (ICH). However, their long-term efficacy and safety remain un...

    Authors: Chen Guo, Yang Bai, Xiaobin Zhang, Pinjing Zhang, Song Han and Di Fan
    Citation: BMC Neurology 2025 25:55
  9. Both vitamin B6 deficiency and vitamin B12 deficiency can present with symptoms that appear like polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome, with painful periphe...

    Authors: Stephan Hu, Sharon Brown-Kunin, Paul Martin and Yujie Wang
    Citation: BMC Neurology 2025 25:54
  10. Cerebral venous sinus thrombosis is a rare stroke with several clinical manifestations. Several studies have identified prognostic risk factors associated with poor functional outcomes and established predicti...

    Authors: Lili Lin, Senfeng Liu, Wei Wang, Xiao-kuo He, Muhammad Hibatullah Romli and Ruthpackiavathy Rajen Durai
    Citation: BMC Neurology 2025 25:52
  11. Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disorder characterized by the presence of inclusions within the nuclei of various cell types. The clinical manifestations of patients ...

    Authors: Yonghong Wang, Yongxiang Li, Wei Pan, Yuezhen Shen, Junxia Li, Ying Liu, Yuhua Peng and Shulai Zhu
    Citation: BMC Neurology 2025 25:51
  12. Alzheimer’s disease (AD) is one of the most common forms of dementia in the elderly, characterized by progressive neurodegeneration. While the exact etiology of AD remains unclear, immune inflammation is known...

    Authors: Linzhu, Jianxin Zhang, Wenhui Fan, Chen Su and Zhi Jin
    Citation: BMC Neurology 2025 25:49
  13. Atherosclerotic diseases are systemic, and stroke patients often present with both intracranial artery stenosis (ICAS) and coronary artery stenosis (COAS). This study aimed to investigate the prevalence of ICA...

    Authors: Gege Zhang, Sijie Dong, Fanfan Feng, Weihao Kan, Taozhen Shi, Hongmei Ding and Ruiguo Dong
    Citation: BMC Neurology 2025 25:48
  14. Early neurological deterioration (END) occurs in individuals who had experienced acute ischemic stroke (AIS), impacting long-term functional outcomes. We aimed to investigate the association between endothelia...

    Authors: Sang Hee Ha, Bo Hye Yoon, Bon Gook Koo, Dong Hoon Shin, Yeong-Bae Lee and Bum Joon Kim
    Citation: BMC Neurology 2025 25:47
  15. Zonulin regulates permeability in blood–brain and intestinal barriers. The pathophysiology of migraine is based on the effect of neurogenic inflammation. The aim of the current investigation was to examine the...

    Authors: Gözde Ülfer, Burcu Polat, Ahmet Yabalak and Çağrı Çakıcı
    Citation: BMC Neurology 2025 25:46
  16. Minimal hepatic encephalopathy (MHE) is one of the most debilitating complications of hepatic cirrhosis, and visual electrophysiology, visual evoked potential (VEP) has long been used for MHE diagnosis. This t...

    Authors: Reem M. Sabry, Osama Hamad, Hossam Eldin Mohamed Khalil, Sahar Ibrahim Mohammed, Ragaey Ahmad Eid and Hanan Hosny
    Citation: BMC Neurology 2025 25:45
  17. Early adequate feeding reduces mortality in patients with acute severe stroke. Supplemental parenteral nutrition (SPN) may address enteral nutrition (EN) deficiency and mitigate the risk of nosocomial infectio...

    Authors: Chen Ma, Zhirong Fan, Xuan Wang, Bian Li, Jingjing Zhao, Xiaogang Kang, Wen Jiang and Fang Yang
    Citation: BMC Neurology 2025 25:44
  18. Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis (Anti-AMPAR-E) is a very rare subtype of autoimmune encephalitis, typically presenting with memory decline, seizures, and changes...

    Authors: Chunxia Yan, Lingling Bai, Jingwei Du, Zonglei Chong, Guangjun Xu and Xiaoqian Yang
    Citation: BMC Neurology 2025 25:43
  19. As the most frequent chronic neurological disorder in young adults, Multiple sclerosis (MS) significantly affects neurological function, particularly the autonomic nervous system. While the physical symptoms a...

    Authors: Reza Dehghaniathar, Ali Faegh, Fahimeh Hajiakhoundi, Behnam Shakiba and Zeynab Najjar
    Citation: BMC Neurology 2025 25:42
  20. Hyponatremia (< 135 mmol/L) is the most common electrolyte disturbance in patients with stroke. However, few studies have reported the relationship between hyponatremia at admission and outcomes in patients wi...

    Authors: Ao Qian, Longyi Zheng, Jia Duan, Lun Li, Wenli Xing and Shuang Tang
    Citation: BMC Neurology 2025 25:41
  21. Childlessness, as well as having a high number of children, has been reported to be associated with an elevated risk of dementia compared to having 2–3 children. The mechanisms underlying these relationships a...

    Authors: Teferi Mekonnen, Vegard Skirbekk, Ekaterina Zotcheva, Bo Engdahl, Bernt Bratsberg, Astanand Jugessur, Catherine Bowen, Geir Selbæk, Hans-Peter Kohler, Jennifer R. Harris, Sarah E. Tom, Steinar Krokstad, Trine Holt Edwin, Yehani Wedatilake, Katrin Wolfova, Dana Kristjansson…
    Citation: BMC Neurology 2025 25:39
  22. Recent research has highlighted the role of fronto-parietal brain networks and cognitive control in mood disorders. Transcranial direct current stimulation (tDCS) and computer-based cognitive training are used...

    Authors: Csaba Kazinczi, Noemi Szepfalusi, Viola Luca Nemeth, Adrienn Holczer, Katalin Jakab, Laszlo Vecsei, Peter Klivenyi, Anita Must and Mihaly Racsmany
    Citation: BMC Neurology 2025 25:38
  23. Malaria is an infectious disease caused by Plasmodium parasites, transmitted to humans by infected female Anopheles mosquitoes. Five Plasmodium species infect humans: P. vivax, P. falciparum, P. ovale, P. mala...

    Authors: Molla Asnake Kebede, Alemayehu Beharu Tekle, Misikir Alemu Eshetu, Erkyehun Pawlos Shash, Melaku Tsediew Berhanu, Elias Tabiet Ahmed and Hashime Meketa Negatie
    Citation: BMC Neurology 2025 25:37
  24. Oxidative damage has been implicated in multiple neurodegenerative diseases, including epilepsy. Selenium, in the form of selenoproteins is an integral part of the human antioxidant defense system. Though a re...

    Authors: Hareem Nisar, Rafat Amin, Sadaf Khan, Tehseen Fatima, Qamar-Un-Nisa and Jawwad-Us-Salam
    Citation: BMC Neurology 2025 25:34
  25. The definition of minor ischemic stroke (MIS) is a topic of debate, however, the most accepted definition is a stroke with National Institutes of Health Stroke Scale (NIHSS) ≤ 5. Intravenous thrombolysis (IVT)...

    Authors: Mostafa Hossam El Din Moawad, Talal Salem, Anas Alaaeldin, Youssef Elaraby, Peter D. Awad, Amr Ahmed Khalifa, Ahmed El Naggar, Khaled Ashraf Mohamed, Mohamed Elhalal, Mostafa Badr and Ramy Abdelnaby
    Citation: BMC Neurology 2025 25:33
  26. Purulent meningitis poses a significant clinical challenge with high mortality. We present the case of a 54-year-old female transferred to our emergency department with suspected bacterial meningitis, later di...

    Authors: Cem Thunstedt, Carla Palleis, Johannes Wischmann, Suzette Heck, Konstantinos Dimitriadis and Matthias Klein
    Citation: BMC Neurology 2025 25:32
  27. Anti-NMDA receptor encephalitis is an autoimmune, antibody-mediated inflammatory disease of the brain characterized by the presence of IgG antibodies targeting the excitatory N-methyl-D-aspartate receptor (NMD...

    Authors: Huasheng Huang, Yizhi Wei, Huihui Qin, Guangshun Han and Jie Li
    Citation: BMC Neurology 2025 25:31
  28. Platelet count and function may be closely related to survival and prognosis of stroke and cancer. However, little is known on the impact of platelet count on the patients with a history of stroke and cancer. ...

    Authors: Yuqi Pei, Wei Ouyang, Peiyun Qi, Zhongjie Yan, Yaoru Li, Xiangjian Zhang, Cong Zhang and Lili Cui
    Citation: BMC Neurology 2025 25:30
  29. Guillain-Barré syndrome (GBS) presents with progressive ascending weakness, but it can also present with dysautonomia such as tachycardia, blood pressure fluctuations, diaphoresis, ileus, and urinary retention...

    Authors: Gerald T. Pagaling, Lowrence Precious C. Dichoso, Nikolai Gil D. Reyes and Mario B. Prado Jr.
    Citation: BMC Neurology 2025 25:29
  30. To evaluate the overall satisfaction, device usability, and injection experience of MS patients self-administering ofatumumab using the Sensoready® autoinjector device in the United States (US).

    Authors: Amy Perrin Ross, Jacqueline Nicholas, Ming-Hui Tai, Stephen Yeung, Nazneen Fatima Shaikh, Helen Chen, Mariana Fernandes, Aaron Cortright and Kevin Hawkins
    Citation: BMC Neurology 2025 25:28
  31. Autoimmune encephalitis associated with anti-GluK2 antibodies is a recently identified condition, typically characterized by cerebellar ataxia. This case report presents a unique clinical manifestation involvi...

    Authors: Zhengping Cheng, Yang Song, Shuqi Zhao, Xiaowen Sui, Lili Xie, Hongling Zhao, Xin Pan, Li Cui, Xinran Huang and Shubei Ma
    Citation: BMC Neurology 2025 25:27
  32. Low-grade glioma (LGG) is a primary brain tumor with relatively low malignancy. NCOA4 is a key regulator of ferritinophagy-related processes and is involved in the occurrence and development of many cancers. H...

    Authors: Guangtang Chen, Xueping Shi, Rukai Jiao, Jiacai Qian, Xiaolin Du, Jian Liu and Xi Zeng
    Citation: BMC Neurology 2025 25:26
  33. Effects of subthalamic nucleus deep brain stimulation (STN-DBS) on neuropsychiatric symptoms of Parkinson’s disease (PD) remain debated. Sensor technology might help to objectively assess behavioural changes a...

    Authors: Lena C. Bruhin, Michael Single, Aileen C. Naef, Katrin Petermann, Mario Sousa, Matilde Castelli, Ines Debove, Marie E. Maradan-Gachet, Andreia D. Magalhães, Andreas A. Diamantaras, M. Lenard Lachenmayer, Gerd Tinkhauser, Julia Waskönig, Christopher M. el Achkar, Alia Lemkaddem, Mathieu Lemay…
    Citation: BMC Neurology 2025 25:25
  34. This study evaluates the comprehensive impact of different exercise interventions on the quality of life in stroke patients through network meta-analysis, aiming to provide scientific evidence for developing m...

    Authors: Liqun Jiang, Huimin Ding, Qishuai Ma, Shang Gao, Xinxin Zhang and Buongo Chun
    Citation: BMC Neurology 2025 25:24
  35. This study aims to evaluate the clinical significance of ultrasound-based measurement of optic nerve sheath diameter (ONSD) in predicting intracerebral hemorrhage (ICH) complicated by cerebral-cardiac syndrome...

    Authors: Wei-Ze Fan, Jun-Rong Jiang, Hui-Ling Zang, Hui Cheng, Xiao-Hui Shen, Wen-Juan Yang, Hui Wang and Li-Xing Jing
    Citation: BMC Neurology 2025 25:23
  36. Delirium is a common complication in patients at the intensive care unit (ICU) and is associated with prolonged ICU-stay and hospitalization and with increased morbidity. The impact of ICU-delirium on long-ter...

    Authors: Ignazio De Trizio, Maria Angeliki Komninou, Jutta Ernst, Reto Schüpbach, Jan Bartussek and Giovanna Brandi
    Citation: BMC Neurology 2025 25:22
  37. Numerous noncontrast computed tomography (NCCT) markers have been reported and validated as effective predictors of hematoma expansion (HE). Our objective was to develop and validate a score based on NCCT mark...

    Authors: Tian-Nan Yang, Xin-Ni Lv, Zi-Jie Wang, Xiao Hu, Li-Bo Zhao, Jing Cheng and Qi Li
    Citation: BMC Neurology 2025 25:21
  38. Sodium–glucose cotransporter-2(SGLT-2) inhibitors are a newer class of antidiabetic drugs with the increased risk of euglycemic diabetic ketoacidosis(EuDKA). Encephalopathy is a rare but life-threatening event...

    Authors: Lulu Chu, Zhenhua Xi, Runzhi Ma, Weiliang Shi and Guoshen Yu
    Citation: BMC Neurology 2025 25:20
  39. Ischemic stroke is a major public health concern, contributing significantly to global morbidity and mortality. Recent studies have suggested that alterations in liver enzymes may be linked to the risk of deve...

    Authors: Omnia Samy El-Sayed, Asmaa Zakria Alnajjar, Abdelfattah Arafa, Hazem E. Mohammed, Abdelrahman M. Elettreby, Safiya Ibraheem, Dalia Esam Tawfik, Menna Allah Ashraf Abdullah and Mohamed Ahmed Tolba
    Citation: BMC Neurology 2025 25:18
  40. Cerebral venous sinus thrombosis (CVST) is a rare yet significant neurological disorder with high mortality. Understanding its evolving characteristics, risk factors, and outcomes, particularly in Chinese pati...

    Authors: Xiaoming Zhang, Kun Fang, Duo Lan, Xiangqian Huang, Xunming Ji, Ran Meng and Da Zhou
    Citation: BMC Neurology 2025 25:17
  41. Sarcoid-like reaction is an immunological reaction that can affect lymph nodes and organs but does not meet the diagnostic criteria for systemic sarcoidosis. Anti-CD20 auto-antibodies have been reported to be ...

    Authors: Joumana Freiha, Effie Grand, Ben Marshall, Ramamurthy Arunchalam, Ashwin Pinto and Chinar Osman
    Citation: BMC Neurology 2025 25:16
  42. Detection of atrial fibrillation (AF) in patients with embolic stroke of undetermined source (ESUS) is important for the secondary prevention of stroke. We investigated the factors associated with the detectio...

    Authors: Jae-Han Bae, Jae-Chan Ryu, Sang Hee Ha, Min Soo Cho, Myung-Jin Cha, Jun Young Chang, Dong-Wha Kang, Sun U. Kwon, Jong S. Kim and Bum Joon Kim
    Citation: BMC Neurology 2025 25:15
  43. This study aimed to investigate the relationship between the unique weather change and acute ischemic stroke (AIS) in the southern Zhejiang Province of China and to provide evidence for better predicting and p...

    Authors: Yao Tong, Yating Chen, Yulong Yu, Faxing Wang, Lina Lin, Gangjian He, Lingyang Chen, Xiuxiu Zhuang, Wenwen Du and Yunchang Mo
    Citation: BMC Neurology 2025 25:14

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